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We generated a retinal pigment epithelial cell line with complete knockout of giantin using CRISPR. This experiment sought to define changes in the transcriptome of that cell line compared to the parental wild-type cells.
ORGANISM(S): Homo sapiens 
The secretion of extracellular matrix (ECM) proteins is vital to the maintenance of tissue health. One 28 major control point of this process is the Golgi apparatus, whose dysfunction causes numerous 29 connective tissue disorders. Golgi function is tightly linked to its structure, which is maintain...
ORGANISM(S): Homo sapiens (Human) 
2025-08-25 | PXD061302 | Pride
The Pseudomonas synxantha strain NCIMB10586 produces the antibiotic mupirocin / Pseudomonic acid A from a 75 kb gene cluster; expression of this is regulated through quorum-sensing. We wished to examine expression of the strain during batch growth, in particular of the mupirocin cluster and any othe...
ORGANISM(S): Pseudomonas synxantha 
Cambridge control samples using a 24k expression array from Illumina
Cambridge control samples using a 660K genotyping chip from Illumina
Cambridge control samples using a 1.2M genotyping chip from Illumina
The aim of this study was to compare the power to detect associations between SNPs using cis-eQTL mapping and ASE analysis (allele specific expression).
Data Access Committee EGAC01000000019
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