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Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis; (TEN) are life-threatening adverse drug reactions characterized; by massive epidermal necrosis, in which the specific danger; signals involved remain unclear. Here we show that blister; cells from skin lesions of SJS-TEN primarily consis...
ORGANISM(S): Homo sapiens 
Based on the prior knowledge of involvement of the human leukocyte antigen locus in Han Chinese patients with carbamazepine-induced Stevens-Johnson syndrome, we imputed the HLA types for each case and control subject from the array of SNPs in the Human610-Quad GWAS platform (NCBI Build 36.1). We the...

The rising global prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD), including its severe form metabolic dysfunction-associated steatohepatitis (MASH), underscores the urgency to elucidate its pathophysiology. To investigate key metabolic interactions central to MASLD...

2026-03-13 | MTBLS14048 | MetaboLights
Ilex x ‘Whoa Nellie’ is a yellow leaf (YT) mutant of I. x ‘Nellie R. Stevens’ (WT), an important ornamental woody species. However, the molecular mechanism of the YT mutant remains unknown. Therefore,we compared yellow-colored mutant leaves and normal green leaves in transcriptomic terms. Our study ...
ORGANISM(S): Ilex 
2025-06-14 | GSE233348 | GEO
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