Stevens W W - OmicsDI

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Unknown (1616)
Transcriptomics (75)
Genomics (29)
Proteomics (14)
Metabolomics (3)
Genomic (1)

Organisms

Homo sapiens (58)
Mus musculus (22)
Arabidopsis thaliana (3)
Escherichia coli str. K-12 substr. MG1655 (2)
Rattus norvegicus (2)
Methanobrevibacter ruminantium (1)
Pantoea stewartii (1)
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 (1)
Vibrio parahaemolyticus (1)
Burkholderia pseudomallei (1)
Skeletonema marinoi (1)
Salmonella enterica subsp. enterica serovar Typhimurium (1)
Solanum tuberosum (1)
Caenorhabditis elegans (1)
Escherichia coli (1)
Gallus gallus (1)
Candida albicans (1)
Bacteria (1)
Influenza A virus (1)
Sus scrofa domesticus (1)
Synechocystis sp. PCC 6803 (1)

Organisms

Escherichia coli str. K-12 substr. MG1655 (1)
Mus musculus (1)

Repository

biostudies-arrayexpress (75)
EGA (27)
pride (10)
MassIVE (3)
MetaboLights (3)
ENA (2)
dbGaP (1)
geo (1)
iProX (1)

Tissue

Cell suspension culture (4)
Plant cell (3)
Root (2)
Rosette (2)
B cell (1)
Blood plasma (1)
Flower (1)
HeLa cell (1)
Leaf (1)
Leukocyte (1)
Liver (1)
Photosynthetic cell (1)
Shoot (1)
Spleen (1)

Disease

Lung cancer (1)
Influenza (1)

Technology Type

Mass Spectrometry (10)
Illumina 15K (8)
Shotgun proteomics (4)
Bottom-up proteomics (3)
Mass spectrometry (2)
Illumina Infinium 1.2M (1)
Unknown (1)
Mass spectrometry assay (1)
Affinity purification coupled with mass spectrometry proteomics (1)
Data-dependent acquisition (1)
Gel-based experiment (1)
SRM/MRM (1)

Instrument Platform

Illumina NovaSeq X (2)
Illumina NovaSeq 6000 (2)
Illumina HiSeq 2000 (2)
Orbitrap Fusion Lumos (2)
Agilent 2100 Bioanalyzer (1)
NextSeq 500 (1)
Q Exactive (1)
Q Exactive Plus (1)
QExactive Plus (1)
Flame ionisation detector MS - (1)
Liquid Chromatography MS - negative - reverse phase (1)
Liquid Chromatography MS - negative - reverse-phase (1)
Liquid Chromatography MS - positive - hilic (1)
Liquid Chromatography MS - positive - reverse phase (1)
Liquid Chromatography MS - positive - reverse-phase (1)

Publication Date

2010 (11)
2015 (10)
2008 (10)
2013 (9)
2009 (7)
2011 (6)
2026 (5)
2014 (5)
2007 (4)
2019 (4)
2021 (3)
2018 (3)
2016 (3)
2023 (3)
2017 (2)
2012 (2)
2025 (2)
2022 (2)
2024 (1)
2004 (1)

CHEBI ID

CHEBI:10049 (1)
CHEBI:10093 (1)
CHEBI:101085 (1)
CHEBI:109895 (1)
CHEBI:1109 (1)
CHEBI:12387 (1)
CHEBI:124991 (1)
CHEBI:125535 (1)
CHEBI:131887 (1)
CHEBI:131924 (1)
CHEBI:132448 (1)
CHEBI:132883 (1)
CHEBI:133026 (1)
CHEBI:133094 (1)
CHEBI:133657 (1)
CHEBI:133662 (1)
CHEBI:133756 (1)
CHEBI:133758 (1)
CHEBI:134092 (1)
CHEBI:134281 (1)
CHEBI:134418 (1)
CHEBI:134442 (1)
CHEBI:134454 (1)
CHEBI:134548 (1)
CHEBI:134583 (1)
CHEBI:135654 (1)
CHEBI:135736 (1)
CHEBI:135876 (1)
CHEBI:135893 (1)
CHEBI:135954 (1)

Metabolite Name

(1'S,2R,2'R,10'S,11'S,15'S)-17'-hydroxy-2',15'-dimethylspiro[oxolane-2,14'-tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane]-6',8'-diene-5,5'-dione (1)
(1-{1-[(4-hydroxy-3-methoxyphenyl)methyl]-7,8-dimethoxy-2,2-dimethyl-1,2,3,4-tetrahydro-2λ⁵-isoquinolin-2-yl}ethylidene)-λ⁴-oxidanyliumyl (1)
(10,14a-dihydroxy-2,2,4a,6a,6b,9,9,12a-octamethyl-docosahydropicen-13-yl)oxidanesulfonic acid (1)
(10S,14S)-10,14,20-trimethyl-16-methylidene-22-azahexacyclo[12.10.0.0²,¹¹.0⁵,¹⁰.0¹⁵,²³.0¹⁷,²²]tetracosan-5-ylium-7-olate (1)
(12aR)-4-(dimethylamino)-4a,5,10,12a-tetrahydroxy-6-methylidene-1,2,3,4,4a,5,5a,6,11,11a,12,12a-dodecahydrotetracene-1,3,11,12-tetrone (1)
(12aR)-7-chloro-4-(dimethylamino)-4,6,10,12a-tetrahydroxy-1,2,3,4,4a,5,5a,6,11,11a,12,12a-dodecahydrotetracene-1,3,11,12-tetrone (1)
(12aS)-4,7-bis(dimethylamino)-10,12,12a-trihydroxy-1,3,11-trioxo-9-(2-oxoacetamido)-1,2,3,4,4a,5,5a,6,11,11a,12,12a-dodecahydrotetracene-2-carboximidic acid (1)
(12aS)-9-{[2-(tert-butylamino)-1-hydroxyethylidene]amino}-4,7-bis(dimethylamino)-5,10,12,12a-tetrahydroxy-1,3,11-trioxo-1,2,3,4,4a,5,5a,6,11,12a-decahydrotetracene-2-carboximidic acid (1)
(13-{[5-(acetyloxy)-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1,6,6,11,15-pentamethyl-14-(6-methylhept-5-en-2-yl)-5-[(3,4,5-trihydroxyoxan-2-yl)oxy]tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-7-en-9-yl)oxidanesulfonic acid (1)
(13R)-5-(3,4-dihydroxyphenyl)-6,9,17,19,21-pentahydroxy-13-(4-hydroxyphenyl)-4,12,14-trioxapentacyclo[11.7.1.0²,¹¹.0³,⁸.0¹⁵,²⁰]henicosa-2(11),3(8),5,9,15,17,19-heptaen-7-one (1)
(15Z)-Octadec-15-en-9,11,13-triynoic acid (1)
(1R)-1,4-bis({[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy})-3-hydroxy-5-(sulfooxy)cyclohexane-1-carboxylic acid (1)
(1R,16Z,24E,26E,28Z)-1,18,26,27-tetrahydroxy-19,30-dimethoxy-12-[1-(3-methoxy-4-oxocyclohexyl)propan-2-yl]-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0⁴,⁹]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone (1)
(1R,16Z,24E,26E,28Z)-1,18-dihydroxy-12-[1-(4-hydroxy-3-methoxycyclohexyl)propan-2-yl]-19,30-dimethoxy-15,17,21,23,29-pentamethyl-35-methylidene-11,36-dioxa-4-azatricyclo[30.3.1.0⁴,⁹]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone (1)
(1R,2R,3R,11S,12S,14R,26R)-5,6',7',12-tetrahydroxy-6-methoxy-7,21,30-trimethyl-27-oxo-3',4'-dihydro-2'H-17,19,28-trioxa-24-thia-13,30-diazaspiro[heptacyclo[12.9.6.1³,¹¹.0²,¹³.0⁴,⁹.0¹⁵,²³.0¹⁶,²⁰]triacontane-26,1'-isoquinoline]-4(9),5,7,15(23),16(20),21-hexaen-22-yl acetate (1)
(1R,2S,3R,4R,5S,6R,7S)-1,3,4,5,7,8,9,10,10-Nonachlorotricyclo[5.2.1.0²,⁶]dec-8-ene (1)
(1R,6S,12R,15S)-5,5-Dimethyl-11,13-dioxatetracyclo[7.5.1.0¹,⁶.0¹²,¹⁵]pentadec-8-ene (1)
(1R,9S,18Z,24R)-12-[1-(4-chloro-3-hydroxycyclohexyl)prop-1-en-2-yl]-17-ethyl-1,14-dihydroxy-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.0⁴,⁹]octacos-18-ene-2,3,10,16-tetrone (1)
(1R,9S,18Z,24R)-12-[1-(4-chloro-3-methoxycyclohexyl)prop-1-en-2-yl]-17-ethyl-1,14-dihydroxy-13-(hydroxymethyl)-23,25-dimethoxy-19,21,27-trimethyl-11,28-dioxa-4-azatricyclo[22.3.1.0⁴,⁹]octacos-18-ene-2,3,10,16-tetrone (1)
(1S)-1,3,4-trihydroxy-5-(sulfooxy)cyclohexane-1-carboxylic acid (1)
(1S,16Z,24E,26E,28Z)-1,18-dihydroxy-12-{1-[4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-15-(hydroxymethyl)-19,30-dimethoxy-17,21,23,29,35-pentamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0⁴,⁹]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone (1)
(1S,16Z,24E,26E,28Z)-1,18-dihydroxy-12-{1-[4-(2-hydroxyethoxy)-5-methoxy-2-oxocyclohexyl]propan-2-yl}-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0⁴,⁹]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone (1)
(1S,2R,10S,11S,14R,15R)-2,15-Dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-7-ene (1)
(1S,2S,10S,11S,15R)-14-(5,6-dimethylheptan-2-yl)-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane-5,17-diol (1)
(1S,2S,5R,7R,10S,11S,14R,15S,17S)-14-[(1R)-1,2-Dihydroxyethyl]-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane-5,14,17-triol (1)
(1S,2S,5S,10R,11S,14R,15R)-14-[(2R,5R)-5-Ethyl-6-methylheptan-2-yl]-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan-5-ol (1)
(1S,2S,7S,10R,15R)-2,15-dimethyl-14-(1,4,6-trihydroxy-6-methylheptan-2-yl)tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane-5,9,16-triol (1)
(1S,5R,13R,17S)-15-[(1S,3S,5R,13R)-10,14-Dimethoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0¹,¹³.0⁵,¹⁷.0⁷,¹⁸]octadeca-7(18),8,10,14,16-pentaen-3-yl]-17-hydroxy-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0¹,¹³.0⁵,¹⁷.0⁷,¹⁸]octadeca-7(18),8,10,15-tetraen-14-one (1)
(2-Aminoethoxy)[(2R)-2-[(1Z,9Z)-octadeca-1,9-dien-1-yloxy]-3-[(6Z,9Z,12Z,15Z)-octadeca-6,9,12,15-tetraenoyloxy]propoxy]phosphinic acid (1)
(2-Aminoethoxy)[(2R)-2-[(5Z,8Z,11Z)-icosa-5,8,11-trienoyloxy]-3-[(9Z)-octadeca-1,9-dien-1-yloxy]propoxy]phosphinic acid (1)

First Public Date

2014 (2)

Classification

bacteria (1)

Study type

Transcription profiling by array (46)
RNA-seq of coding RNA (15)
Comparative genomic hybridization by array (4)
Unknown experiment type (2)
Other (2)
Methylation profiling by array (2)
RNA-seq of coding RNA from single cells (2)
MicroRNA profiling by high throughput sequencing (1)

Release Date

2024 (156)
2021 (151)
2022 (149)
2023 (147)
2025 (143)
2020 (120)
2019 (112)
2015 (110)
2018 (101)
2016 (72)
2017 (68)
2013 (68)
2012 (52)
2014 (51)
2011 (43)
2010 (42)
2009 (42)
2008 (22)
2026 (18)
2007 (9)
2005 (6)
2004 (3)
2006 (3)
1998 (2)
2003 (1)

Lab affiliation

ARC Centre of Excellence in Plant Cell Walls School of BioSciences The University of Melbourne Australia (1)
Department of Biochemistry University of Cambridge Cambridge UK (1)
Department of Biochemistry University of Cambridge Cambridge UK CB2 1GA (1)
Department of Molecular Biology, Princeton University, US (1)
Dept. Biochemistry, Cambridge University, UK (1)
Duke University Dept of Medicine (1)
Infection and Immunity Program, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia (1)
Institute for Cell and Molecular Biology, Department of Molecular Biosciences 2500 Speedway, MBB 3.312B Austin, TX 78712-1095, USA (1)
Medical Research Council - Laboratory of molecular biology (1)
Utrecht University (1)

Tags

xref:PubMed:17913887 (1)
xref:PubMed:19767843 (1)
pathogen:bacterium (1)
pathogen (1)

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Transcription profiling of human Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis patients blister cells from skin lesions reveals these consist of cytotoxic T cells annd NK cells

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis; (TEN) are life-threatening adverse drug reactions characterized; by massive epidermal necrosis, in which the specific danger; signals involved remain unclear. Here we show that blister; cells from skin lesions of SJS-TEN primarily consis...

ORGANISM(S): Homo sapiens

2009-01-13 | E-GEOD-13727 | biostudies-arrayexpress

Research Directions in Genetic Predispositions to Stevens-Johnson Syndrome / Toxic Epidermal Necrolysis.

Not available

S-EPMC5805563 | biostudies-literature

Case report: Alpelisib-induced Stevens-Johnson syndrome.

Not available

S-EPMC9554210 | biostudies-literature

A bioinformatic approach to identify pathogenic variants for Stevens-Johnson syndrome.

Not available

S-EPMC10326529 | biostudies-literature

HLA-A*3101 and Carbamazepine-Induced Hypersensitivity Reactions in Europeans

Based on the prior knowledge of involvement of the human leukocyte antigen locus in Han Chinese patients with carbamazepine-induced Stevens-Johnson syndrome, we imputed the HLA types for each case and control subject from the array of SNPs in the Human610-Quad GWAS platform (NCBI Build 36.1). We the...

EGAS00000000036 | EGA

Culprit Medications and Risk Factors Associated with Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: Population-Based Nested Case-Control Study.

Not available

S-EPMC8814784 | biostudies-literature

Associations Between Repetitive Negative Thinking and Habituation of Defensive Responding Within and Between Sessions.

Not available

S-EPMC9537406 | biostudies-literature

Superficial mucoceles as a sequel to Stevens‑Johnson syndrome during treatment of cutaneous squamous cell carcinoma with cemiplimab: A case report and review of literature.

Not available

S-EPMC11609618 | biostudies-literature

Adverse drug reaction causality assessment tools for drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: room for improvement.

Not available