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ProteomicsProteomic analyses of urinary exosomes identify heparanase, cathepsin C, 2-macroglobulin and sarcoplasmic endoplasmic Ca2+ ATPase-3 (SERCA3) as potential biomarkers for early diagnosis of sickle nephropathy
Sickle cell disease-induced nephropathy (SCN) is a leading cause of morbidity and mortality in sickle cell disease (SCD). Early intervention is crucial for mitigating its effects. However, current diagnostic methods rely on non-specific tests and may not detect SCN until renal damage has become irre...
ORGANISM(S): Mus Musculus (mouse) 
2024-02-07 | PXD043401 | JPOST Repository
ProteomicsLarge-scale Multi-omic Analysis of COVID-19 Severity
We performed RNA-Seq and high-resolution mass spectrometry on 128 blood samples from COVID-19 positive and negative patients with diverse disease severities. Over 17,000 transcripts, proteins, metabolites, and lipids were quantified and associated with clinical outcomes in a curated relational datab...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-07-08 | MSV000085703 | MassIVE
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