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STING is an evolutionarily conserved key regulator of innate immunity. In mammals, STING activates two distinct signaling pathways, the IRF3 and the NF-κB pathways, which act in conjunction to drive antiviral immunity. While the molecular mechanism of STING-mediated IRF3 activation has been untangle...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2026-04-09 | PXD054811 | Pride
STING signalling compensates for low tumour mutation burden to drive anti-tumour immunity
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