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GenomicsSubsets of NFkappaB-dependent genes are differentially regulated after combined treatment with hyperthermia and cytokine
Heat shock transcription factor 1 (HSF1) is responsible for triggering stress-induced activation of the HSP genes. HSF1 is also involved in the regulation of many other genes associated with multiple cellular processes including cell signaling, development, fertility, cell death and metabolism, e.g....
ORGANISM(S): Homo sapiens 
2015-08-01 | E-GEOD-60984 | biostudies-arrayexpress
TranscriptomicsPotential biomarkers of non-obstructive azoospermia identified in microarray gene expression analysis
We analyzed gene expression profiles of human testicular biopsies in men with idiopathic nonobstructive azoospermia. Using new generation oligonucleotide microarray platform GeneChipM-BM-. Human Gene 1.0 ST, we identified genes which could be potential biomarkers of azoospermia and molecular indica...
ORGANISM(S): Homo sapiens 
2013-09-16 | E-GEOD-45885 | biostudies-arrayexpress
TranscriptomicsThe gene expression analysis of paracrine/autocrine factors in patients with spermatogenetic failure compared to normal spermatogenesis
The role of paracrine/autocrine factors in inflammation, immune response and tumor development is well established. There is also an evidence that some of the cytokines there involved may participate in the regulation of the male gonads. However, their involvement in pathogenesis of male infertilit...
ORGANISM(S): Homo sapiens 
2013-08-02 | E-GEOD-45887 | biostudies-arrayexpress
TranscriptomicsPotential biomarkers tah could help to determine the prognosis of azoospermia treatment
We analyzed gene expression profiles of human testicular biopsies in men with idiopathic nonobstructive azoospermia who underwent therapy with hCG/rFSH. Using new generation oligonucleotide microarray platform GeneChip® Human Gene 1.0 ST, we identified genes which could be potential prognostic bio...
ORGANISM(S): Homo sapiens 
2015-12-31 | E-GEOD-51111 | biostudies-arrayexpress
TranscriptomicsTranscriptomic profiling of patient-derived endometrial cancer organoids (Berg HF)
Patient-derived endometrial cancer organoids. The data was used to compare gene expression profile between organoids, and to explore whether an organoid-derived gene signature could predict disease outcomes in independent patient cohorts.
ORGANISM(S): Homo sapiens 
2021-07-16 | E-MTAB-10664 | biostudies-arrayexpress
TranscriptomicsTranscriptomic profiling of endometrial primary tumors
Fresh tumor tissue from primary endometrial tumors. Technology: L1000 is an array based technology that measured 978 landmark genes that are extrapolated using an algorithm to generate a transcription profile of 12,328 genes. Reference L1000 technology: Subramanian A, et al. A Next Generation Conne...
ORGANISM(S): Homo sapiens 
2021-07-06 | E-MTAB-10668 | biostudies-arrayexpress
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