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ProteomicsSpatial proteomics reveals differences in the cellular architecture of antibody-producing CHO and plasma-cell derived cells
Most of the recombinant biotherapeutics employed today to combat severe illnesses e.g. various types of cancer or autoimmune diseases are produced by Chinese hamster ovary (CHO) cells. To meet the growing demand of these pharmaceuticals, CHO cells are under constant development in order to enhance t...
ORGANISM(S): Mus musculus (Mouse) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2022-08-02 | PXD029115 | Pride
Machine learning Chinese hamster ovary Subcellular proteomics Mass spectrometry Myeloma 
ProteomicsA small RNA and its involvement in zinc transport
The function and mode of action of small regulatory RNAs is currently still understudied in archaea. In the halophilic archaeon H. volcanii a plethora of sRNAs have been identified, however, in-depth functional analysis is missing for most of them. We selected a small RNA (s479) from H. volcanii for...
ORGANISM(S): Haloferax volcanii (Halobacterium volcanii) 
2021-08-10 | PXD022750 | Pride
Proteomics Abc transporter Archaea Metallostasis Transcriptomics Small rnas 
TranscriptomicsTranscriptional profiling of Blochmannia floridanus during different host stages
The transcriptome of Blochmannia floridanus, the endosymbiont of the carpenter ant Camponotus floridanus, is presented during eight developmental stages of its holometabolous host by use of a whole genome DNA-macroarray. The detected transcription patterns indicate the presence of local transcriptio...
ORGANISM(S): Candidatus Blochmannia floridanus 
2008-11-09 | E-GEOD-12148 | biostudies-arrayexpress
UnknownThe brain hierarchically represents the past and future during multistep anticipation.
Not available
S-EPMC11496687 | biostudies-literature
TranscriptomicsChanges in global gene expression in lung cancer cell lines A549 (A) and HTB56 (H) [Affymetrix microarrays]
Here, we analyzed global gene expression changes that were associated with pro-metastatic phenotypes in non-small cell lung cancer using the Affymetrix microarray platform. Changes in global gene expression were determined with Affymetrix microarrays in lung cancer cell lines A549 (A) and HTB56 (H)....
ORGANISM(S): Homo sapiens 
2013-12-18 | E-GEOD-52143 | biostudies-arrayexpress
TranscriptomicsListeria monocytogenes EGD and EGD-e
Transcriptional profile after growth in MM (minimal medium (Premaratne et al. 2001) supplemented with 50 mM Glucose. Note: strain "EGD" has not been deposited at ATCC/NCTC. It is a derivative of the original Murray strain (Murray et al. 1926), obtained from S.H.E. Kaufmann. Strain "E...
ORGANISM(S): Listeria monocytogenes 
2008-11-30 | E-GEOD-12146 | biostudies-arrayexpress
TranscriptomicsExamination of genome-wide methylation changes in lung cancer cell lines A549 (A) and HTB56 (H) [HumanMethylation27 BeadChip experiments]
Cancer cell phenotypes are partially determined by epigenetic specifications such as DNA methylation. Metastasis development is a late event in cancerogenesis and might be associated with epigenetic alterations. Here, we analyzed genome wide DNA methylation changes that were associated with pro-meta...
ORGANISM(S): Homo sapiens 
2013-12-18 | E-GEOD-52144 | biostudies-arrayexpress
UnknownChanges in global gene expression in lung cancer cell lines A549 (A) and HTB56 (H) [Affymetrix microarrays]
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-52143 | biostudies-other
ProteomicsThe response of Haloferax volcanii to salt and temperature stress: a proteome study by label-free mass spectrometry
We performed an in-depth proteome analysis of the haloarchaeal model organism Haloferax volcanii under standard, low and high salt and low and high temperature conditions using label-free mass spectrometry. Qualitative analysis of protein identification data from high pH/reversed phase fractionated ...
ORGANISM(S): Haloferax volcanii DS2 
2019-09-04 | PXD011056 | Pride
Swath Haloferax volcanii Mass spectrometry Stress response Archaea Proteome 
GenomicsExamination of genome-wide methylation changes in lung cancer cell lines A549 (A) and HTB56 (H) [RRBS-Seq experiments]
Cancer cell phenotypes are partially determined by epigenetic specifications such as DNA methylation. Metastasis development is a late event in cancerogenesis and might be associated with epigenetic alterations. Here, we analyzed genome wide DNA methylation changes that were associated with pro-meta...
ORGANISM(S): Homo sapiens 
2013-12-18 | E-GEOD-52140 | biostudies-arrayexpress
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