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ProteomicsProteomic profiling of two distinct populations of extracellular vesicles isolated from human seminal plasma indicates their biogenesis by prostate epithelial cells and potential as biomarker for prostate cancer
Body fluids contain many populations of extracellular vesicles (EV) that differ in size, cellular origin, molecular composition, and biological activities. EV in seminal plasma are in majority originating from prostate epithelial cells, and hence are also referred to as prostasomes. Nevertheless, EV...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD021192 | Pride
Extracellular vesicles  prostasomes  proteomic  subtypes  seminal fluid 
ProteomicsA novel and simple strategy to isolate extracellular vesicles from human plasma and tissue culture medium with high yield and purity
Extracellular vesicles (EVs) function in intercellular communication and can be indicative of the biological status of their producing cells, for example in disease. Isolation of EVs from blood or tissue culture medium is instrumental for the discovery of novel EV associated disease biomarkers as we...
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD015283 | Pride
Extracellular vesicles  exosomes  isolation  lipoprotein particles  human plasma 
TranscriptomicsEndothelial cells require miR-214 to secrete exosomes that suppress senescence and induce angiogenesis in human and mouse endothelial cells
Signalling between endothelial cells, endothelial progenitor cells and stromal cells is crucial for the establishment and maintenance of vascular integrity and involves exosomes, among other signalling pathways. Exosomes are important mediators of intercellular communication in immune signalling, tu...
ORGANISM(S): Homo sapiens 
2013-03-22 | E-GEOD-45375 | biostudies-arrayexpress
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