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TranscriptomicsTranscription profiling of macaque prefrontal cortex treated with MPTP
MPTP treated Macaca fascicularis prefrontal cortices compared to saline treated and untreated controls Experiment Overall Design: Macaques injected daily with Experiment Overall Design: MPTP hydrochloride (0.2 mg/kg, or with saline. Each group consisted of
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-4550 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of C. elegans rrf-3 and eri-1 mutants
RRF-3 and ERI-1 are first identified proteins required for accumulation of at least some endogenous secondary siRNAs in C.elegans. Genome wide gene expression analysis was performed on L4 stage rrf-3 and eri-1 mutant C. elegans to study effects caused by loss of these proteins. Mutant rrf-3 and eri-...
ORGANISM(S): Caenorhabditis elegans 
2008-06-16 | E-GEOD-8659 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human full-term placenta from smokers and non-smokers
Gene expression in placenta from 5 smoking and 5 non-smoking mothers analyzed by Affymetrix Hg133_plus2 microarrays. Experiment Overall Design: Gene expression in placenta from 5 smoking and 5 non-smoking mothers analyzed by Affymetrix Hg133_plus2 microarrays.
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7434 | biostudies-arrayexpress
TranscriptomicsAdult and neonatal astrocytes exhibit diverse gene expression profiles during exposure to beta amyloid ex vivo
Research regarding the role of astrocytes as M-NM-2-amyloid (AM-NM-2) degrading cells has broadened our view about the mechanisms how these common glia cells function in AlzheimerM-bM-^@M-^Ys disease (AD). Based on previous studies adult mouse astrocytes are able to degrade AM-NM-2 deposits from AD ...
ORGANISM(S): Mus musculus 
2012-07-13 | E-GEOD-29317 | biostudies-arrayexpress
TranscriptomicsBone marrow-derived stromal cells from double transgenic rats (of Sprague-Dawley origin) harboring the human angiotensinogen and human renin genes, and control rats
Hypertension and persistent activation of the renin-angiotensin system (RAS) are predisposing factors for development of acute kidney injury (AKI). Although bone marrow-derived stromal cells (BMSCs) have shown therapeutic promise in treatment of AKI, the impact of pathological RAS on BMSC functional...
ORGANISM(S): Rattus norvegicus 
2014-03-31 | E-GEOD-51593 | biostudies-arrayexpress
TranscriptomicsAhR mutant vs N2 wild-type C.elegans, in L1 larval stage
Expression profiles of AhR mutant vs N2 wild-type C.elegans, in L1 larval stage compared by using 23232 feature WUSTL microarray 4 ahr-mutant worm samples compared to 3 wild-type samples. Total RNAs purified and reverse transcribed to cDNA and labeled with Cy3-dUTP, and then hybridized on microarray...
ORGANISM(S): Caenorhabditis elegans 
2010-05-16 | E-GEOD-16036 | biostudies-arrayexpress
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