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GenomicsVitamin C induces Tet-dependent DNA demethylation in ES cells to promote a blastocyst-like methylome [MeDIP-Seq]
DNA methylation is a heritable epigenetic modification involved in gene silencing, imprinting, and the suppression of retrotransposons. Global DNA demethylation occurs in the early embryo and the germline and may be mediated by Tet (ten-eleven-translocation) enzymes, which convert 5-methylcytosine (...
ORGANISM(S): Mus musculus 
2013-06-30 | E-GEOD-46402 | biostudies-arrayexpress
TranscriptomicsVitamin C induces Tet-dependent DNA demethylation in ES cells to promote a blastocyst-like methylome [Affymetrix]
DNA methylation is a heritable epigenetic modification involved in gene silencing, imprinting, and the suppression of retrotransposons. Global DNA demethylation occurs in the early embryo and the germline and may be mediated by Tet (ten-eleven-translocation) enzymes, which convert 5-methylcytosine (...
ORGANISM(S): Mus musculus 
2013-06-30 | E-GEOD-46319 | biostudies-arrayexpress
ModelsBenedict2011 - Genome-scale metoblic network of Methanosarcina acetivorans (iMB745)
Benedict2011 - Genome-scale metoblic network of Methanosarcina acetivorans (iMB745) This model is described in the article: Genome-scale metabolic reconstruction and hypothesis testing in the methanogenic archaeon Methanosarcina acetivorans C2A. Benedict MN, Gonnerman MC, Metc...
2024-10-15 | BIOMD0000001097 | BioModels
FROG 
TranscriptomicsExpression data from rat tumors formed by 9L.EV or 9L.EGFRvIII cells
Analysis of rat tumor xenografts revealed genes that are upregulated in tumors expressing EGFRvIII 12 rats received intracranial injections of 9L cells expressing EGFRvIII or an empty vector control. Three weeks after implantation and subsequent growth, tumors were aseptically removed, processed fo...
ORGANISM(S): Rattus norvegicus 
2015-09-08 | E-GEOD-51147 | biostudies-arrayexpress
ProteomicsBioremediation of a common product of food processing by a human gut bacterium
Bioremediation of a common product of food processing by a human gut bacterium
ORGANISM(S): Mus Musculus (ncbitaxon:10090) Microbiome 
2019-08-27 | MSV000084239 | MassIVE
MetabolomicsER stress inhibits liver fatty acid oxidation while unmitigated stress leads to anorexia-induced lipolysis and both liver and kidney steatosis
The unfolded protein response (UPR), induced by endoplasmic reticulum (ER) stress, regulates the expression of factors that restore protein folding homeostasis. However, in the liver and kidney, ER stress also leads to lipid accumulation, accompanied at least in the liver by transcriptional suppress...
2017-06-23 | MTBLS472 | MetaboLights
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