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TranscriptomicsExpression analysis of murine bone marrow (BMDM) derived macrophages stimulated with C1q
Investigation of whole genome gene expression level changes in BMDM adhered for 4 or 18hrs to Lab Tek Chamber slides pre-coated with 4ug/ml of human serum albumin (HSA) (control protein) or purified human C1q and treated with lipopolysaccharide (LPS: 20ng/ml) Mycobacterium avium 101 (M avium) or apo...
ORGANISM(S): Mus musculus 
2012-03-01 | GSE35280 | GEO
TranscriptomicsExpression analysis of murine bone marrow (BMDM) derived macrophages stimulated with C1q
Investigation of whole genome gene expression level changes in BMDM adhered for 4 or 18hrs to Lab Tek Chamber slides pre-coated with 4ug/ml of human serum albumin (HSA) (control protein) or purified human C1q and treated with lipopolysaccharide (LPS: 20ng/ml) Mycobacterium avium 101 (M avium) or ap...
ORGANISM(S): Mus musculus 
2012-03-01 | E-GEOD-35280 | biostudies-arrayexpress
UnknownDesigning and Validating a Novel Method for Assessing Delay Discounting Associated With Health Behaviors: Ecological Momentary Assessment Study.

Background

Delay discounting quantifies an individual's preference for smaller, short-term rewards over larger, long-term rewards and represents a transdiagnostic factor associated with numerous adverse health outcomes. Rather than a fixed trait, delay discounting may vary over time and plac...
S-EPMC10933719 | biostudies-literature
UnknownClimate Effects on Belowground Tea Litter Decomposition Depend on Ecosystem and Organic Matter Types in Global Wetlands.
Patchy global data on belowground litter decomposition dynamics limit our capacity to discern the drivers of carbon preservation and storage across inland and coastal wetlands. We performed a global, multiyear study in over 180 wetlands across 28 countries and 8 macroclimates using standardized litt...
S-EPMC11636250 | biostudies-literature
UnknownPolyamines delay leaf maturation in low-alkaloid tobacco varieties.
The development of low-alkaloid (LA) tobacco varieties is an important target in the tobacco breeding industry. However, LA Burley 21 plants, in which the Nic1 and Nic2 loci controlling nicotine biosynthesis are deleted, are characterized by impaired leaf maturation that leads to poor leaf quality b...
S-EPMC6508808 | biostudies-literature
UnknownSpatiotemporal spread of Plasmodium falciparum mutations for resistance to sulfadoxine-pyrimethamine across Africa, 1990-2020.

Background

Sulfadoxine-pyrimethamine (SP) is recommended in Africa in several antimalarial preventive regimens including Intermittent Preventive Treatment in pregnant women (IPTp), Intermittent Preventive Treatment in infants (IPTi) and Seasonal Malaria Chemoprevention (SMC). The effectivene...
S-EPMC9371298 | biostudies-literature
UnknownA general pattern of trade-offs between ecosystem resistance and resilience to tropical cyclones.
Tropical cyclones drive coastal ecosystem dynamics, and their frequency, intensity, and spatial distribution are predicted to shift with climate change. Patterns of resistance and resilience were synthesized for 4138 ecosystem time series from n = 26 storms occurring between 1985 and 2018 in ...
S-EPMC8890713 | biostudies-literature
UnknownREVEAL-1, a phase 2 dose regimen optimization study of vosaroxin in older poor-risk patients with previously untreated acute myeloid leukaemia.
This phase 2 study (N = 116) evaluated single-agent vosaroxin, a first-in-class anticancer quinolone derivative, in patients ≥60 years of age with previously untreated unfavourable prognosis acute myeloid leukaemia. Dose regimen optimization was explored in sequential cohorts (A: 72 mg/m(2)  d 1, 8,...
S-EPMC4354261 | biostudies-literature
UnknownImpact of nicotine pathway downregulation on polyamine biosynthesis and leaf ripening in tobacco.
Traditional breeding and molecular approaches have been used to develop tobacco varieties with reduced nicotine and secondary alkaloid levels. However, available low-alkaloid tobacco varieties have impaired leaf quality likely due to the metabolic consequences of nicotine biosynthesis downregulation...
S-EPMC8156150 | biostudies-literature
GenomicsMus musculus
Expression analysis of murine bone marrow (BMDM) derived macrophages stimulated with C1q
PRJNA151573 | ENA
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