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UnknownAssessing competency in less invasive surfactant administration: simulation-based validity evidence for the LISA-AT scores.
Not available
S-EPMC12507647 | biostudies-literature
MetabolomicsCharacterisation and localisation of plant metabolites involved in pharmacophagy in the turnip sawfly

Several herbivorous insects consume certain metabolites from plants for other purposes than nutrition, such as defence. Adults of the turnip sawfly, Athalia rosae take up specific terpenoids, called clerodanoids, from Ajuga reptans. These metabolites are slightly modified by the...

2023-10-30 | MTBLS7508 | MetaboLights
MetabolomicsLarge neutral amino acid levels tune perinatal neuronal excitability and survival
Surprisingly little is known about the critical metabolic changes that neural cells have to undergo during development and how even mild, temporary shifts in this program can influence brain circuitries and behavior. Inspired by the discovery that mutations in SLC7A5, a transporter of metabolically-...
2023-03-28 | MTBLS6578 | MetaboLights
MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
MetabolomicsSex-specific effects of CD248 on metabolism and the adipose tissue lipidome

Cd248 has recently been associated with adipose tissue physiology, demonstrated by reduced weight gain in high fat diet-fed mice with genetic deletion of Cd248 relative to controls. Here we set out to determine the metabolic consequences of loss of Cd248. Strikingly, we find these to be sex speci...

2023-01-05 | MTBLS6615 | MetaboLights
MetabolomicsImmune Stimulation via Wounding Alters Chemical Profiles of Adult Tribolium castaneum
Group-living individuals experience immense risk of disease transmission and parasite infection. In social and in some non-social insects, disease control with immunomodulation arises not only via individual immune defenses, but also via infochemicals such as contact cues and (defensive) volatiles t...
2023-04-24 | MTBLS2277 | MetaboLights
MetabolomicsMicrobial community-scale metabolic modelling predicts personalized short-chain fatty acid production profiles in the human gut
Microbially derived short-chain fatty acids (SCFAs) in the human gut are tightly coupled to host metabolism, immune regulation and integrity of the intestinal epithelium. However, the production of SCFAs can vary widely between individuals consuming the same diet, with lower levels often associated ...
2026-05-26 | MTBLS2308 | MetaboLights
MetabolomicsFatal COVID-19 pulmonary disease involves ferroptosis.

SARS-CoV-2 infection causes severe pulmonary manifestations, with poorly understood mechanisms and limited treatment options. Hyperferritinemia and disrupted lung iron homeostasis in COVID-19 patients imply that ferroptosis, an iron-dependent cell death, may occur. Immunostaining and lipidomic an...

2024-07-11 | MTBLS3107 | MetaboLights
UnknownEvaluating the clinical utility of semi-quantitative luciferase immunosorbent assay using Treponema pallidum antigens in syphilis diagnosis and treatment monitoring.
Not available
S-EPMC11100446 | biostudies-literature
UnknownCurriculum and assessment tool for less invasive surfactant administration: an international Delphi consensus study.
Not available
S-EPMC10444608 | biostudies-literature
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