Sort   by:  
 Page size 
TranscriptomicsSingle cell RNA-seq of human CD8+ T cells binding the IAV HLA-A24/PB1 498-505 tetramer
PBMCs from 4 donors were stained with the influenza A virus HLA-A24/PB1 498-505 tetramer. Two donors (non-LIFT8 and non-LIFT12) showed TCR independent KIR binding to tetramers whereas the other two donors (Non-LIFT14 and Non-LIFT10) showed TCR specific binding. Cells were single-cell sorted on a BD ...
ORGANISM(S): Homo sapiens 
2021-04-08 | E-MTAB-10109 | biostudies-arrayexpress
TranscriptomicsRNA-seq of purified T cells treated with KY1044 + anti-CD3 against anti-CD3 treated controls
KY1044 is a human monoclonal IgG1 that selectively binds to Inducible T cell CO-stimulator (ICOS). The co-stimulatory effect of KY1044-stimulated human T cells was analysed by RNA sequencing (RNA seq). Purified pre-activated (ICOS+ve) T cells were stimulated with either KY1044 and anti-CD3 or anti-C...
ORGANISM(S): Homo sapiens 
2020-09-01 | E-MTAB-9500 | biostudies-arrayexpress
TranscriptomicsGene expression by human splenic B-cell subsets
Enhanced secondary Ab responses are a vital component of adaptive immunity, yet little is understood about the intrinsic and extrinsic regulators of naïve and memory B cells that results in differences in their responses to Ag. Microarray analysis, together with surface and intracellular phenotyping...
ORGANISM(S): Homo sapiens 
2008-12-30 | E-GEOD-13411 | biostudies-arrayexpress
ProteomicsPhospo-proteomic profiling of Castration Resistant Prostate Cancer
The integration of diverse ‘omic’ datasets will increase our understanding of the key signaling pathways that drive disease. Here, we used clinical tissue cohorts corresponding to lethal metastatic castration resistant prostate cancer (CRPC) obtained at rapid autopsy to integrate mutational, transcr...
ORGANISM(S): Homo sapiens (Human) 
2016-08-19 | PXD002286 | Pride
Prostate cancer Human Phosphorylation 
UnknownPhosphoproteome Integration Reveals Patient-Specific Networks in Prostate Cancer.
Not available
S-EPMC4985183 | biostudies-literature
ProteomicsPhospo-proteomic profiling of Castration Resistant Prostate Cancer
The integration of diverse ‘omic’ datasets will increase our understanding of the key signaling pathways that drive disease. Here, we used clinical tissue cohorts corresponding to lethal metastatic castration resistant prostate cancer (CRPC) obtained at rapid autopsy to integrate mutational, transcr...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080776 | MassIVE
TranscriptomicsGene Expression differences in Hepatic Parenchyma and Portal Tracts in Hepatitis C Virus Infected Subjects with High and Low Fibrosis
Background & Aims: Chronic hepatitis C virus (HCV) infection is complicated by hepatic fibrosis. Hypothesizing that fibrogenic signals may originate in cells susceptible to HCV infection, gene expression of hepatocytes was analyzed from persons with chronic HCV at different stages of liver fibrosi...
ORGANISM(S): Homo sapiens 
2013-08-13 | E-GEOD-33650 | biostudies-arrayexpress
TranscriptomicsA novel recurrent mutation in MITF predisposes to familial and sporadic melanoma
We identified a novel germline mutation of the microphthalmia-associated transcription factor (MITF - E318K). This mutation was found to be present in numerous melanoma families, as well as the general population, where its association with melanoma has a significant effect. We determined the effe...
ORGANISM(S): Homo sapiens 
2011-12-01 | E-GEOD-31269 | biostudies-arrayexpress
UnknownGenomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.
Not available
S-EPMC6425931 | biostudies-literature
UnknownComprehensive genomic characterization of squamous cell lung cancers.
Not available
S-EPMC3466113 | biostudies-literature
Sort   by:  
 Page size