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Genomics5-hydroxymethylcytosine: the sixth DNA base
We performed a meta analysis of publicly available TET1, 5mC, 5hmC and genome wide bisulfite profiling data mostly from mouse embryonic stem cells (ESC). Genome wide chromatin immunoprecipitation combined with deep sequencing (ChIP-seq) has revealed binding of the TET1 protein at CpG-island (CGI) pr...
ORGANISM(S): Mus musculus 
2011-11-24 | E-GEOD-31343 | biostudies-arrayexpress
TranscriptomicsDynamic histone H3 epigenome marking during the intraerythrocytic cycle of P. falciparum
This SuperSeries is composed of the following subset Series: GSE15728: Mapping of H3, H3K4me3, H3K9me3, and H3K9ac on mixed asexual stages of P. falciparum GSE16095: Mapping of H3, H3K4me3 and H3K9ac on Ring and Schizont stages of P. falciparum Refer to individual Series
ORGANISM(S): Plasmodium falciparum 
2010-05-19 | E-GEOD-16096 | biostudies-arrayexpress
GenomicsOncofusion protein AML1-ETO targets ERG factor binding sites in AML
ERG has been identified as an essential factor for the function and maintenance of adult hematopoietic stem cells and high ERG expression is a negative prognostic marker for treatment outcome in AML. The molecular function of ERG and its interplay with other factors is however largely unknown. Here ...
ORGANISM(S): Homo sapiens 
2012-09-18 | E-GEOD-23730 | biostudies-arrayexpress
TranscriptomicsMapping of H3, H3K4me3 and H3K9ac on Ring and Schizont stages of P. falciparum
Epigenome profiling has led to the paradigm that promoters of active genes are decorated with H3K4me3 and H3K9ac marks. These data on synchronized parasites reveals significant developmental stage specificity of the epigenome. In rings, H3K4me3 and H3K9ac are homogenous across the genes marking acti...
ORGANISM(S): Plasmodium falciparum 
2010-05-19 | E-GEOD-16095 | biostudies-arrayexpress
TranscriptomicsMapping of H3, H3K4me3, H3K9me3, and H3K9ac on mixed asexual stages of P. falciparum
Epigenome profiling has led to the paradigm that promoters of active genes are decorated with H3K4me3 and H3K9ac marks. Data revealed an extensively euchromatic epigenome with heterochromatin restricted to variant surface antigen gene families (VSA) and a number of genes hitherto unlinked to VSA. Th...
ORGANISM(S): Plasmodium falciparum 
2010-05-19 | E-GEOD-15728 | biostudies-arrayexpress
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