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TranscriptomicsTranscription profiling of mouse RARgamma responsive genes in F9 teratocarcinoma cells
We compared the differentially expressed genes between the F9 Wt cells and F9 RAR gamma knock out cells before and after RA treatment. 3 replicates for each conditions. We also identified the RA responsive genes in the F9 Wt cells. Experiment Overall Design: F9 wt cells and F9 RAR gamma knock out ce...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-8431 | biostudies-arrayexpress
UnknownChitosan/Silver Nanoparticle/Graphene Oxide Nanocomposites with Multi-Drug Release, Antimicrobial, and Photothermal Conversion Functions.
Not available
S-EPMC8124926 | biostudies-literature
UnknownAssociations between 25-hydroxyvitamin D/calcium/alkaline phosphatase levels and the risk of developing kidney stones: Results from NHANES (2013-2018)-based and Mendelian randomization studies.
Not available
S-EPMC11771664 | biostudies-literature
TranscriptomicsDiscovery of genes regulated by the metastasis suppressor gene, RhoGDI2
A number of studies find that metastasis suppressor proteins, including RhoGDI2, may function in part though controlling expression of genes regulating metastasis (reviewed in Smith and Theodorescu, Nature Reviews Cancer, 2009, PMID: 19242414). To uncover systematically gene expression patterns depe...
ORGANISM(S): Homo sapiens 
2012-04-14 | E-GEOD-35014 | biostudies-arrayexpress
UnknownDysfunctional Interaction Between the Dorsal Attention Network and the Default Mode Network in Patients With Type 2 Diabetes Mellitus.
Not available
S-EPMC8741406 | biostudies-literature
TranscriptomicsD-2-Hydroxyglutarate produced by mutant IDH2 causes cardiomyopathy and neurodegeneration in mice
Mutations in isocitrate dehydrogenase 1 and 2 (IDH1/2) have been discovered in several cancer types and cause the neurometabolic syndrome D2-Hydroxyglutaric aciduria (D2HGA). The mutant enzymes exhibit neomorphic activity resulting in production of D2- hydroxyglutaric acid (D-2HG). To study the pat...
ORGANISM(S): Mus musculus 
2014-03-01 | E-GEOD-54838 | biostudies-arrayexpress
TranscriptomicsHDAC Inhibitors induce tumor cell-selective pro-apoptotic transcriptional responses.
The identification of recurrent somatic mutations in genes encoding epigenetic enzymes, coupled with biochemical studies demonstrating aberrant recruitment of epigenetic enzymes such as histone deacetylases (HDACs) and histone methyltransferases (HMTs) to promoter regions through association with on...
ORGANISM(S): Homo sapiens 
2013-04-22 | E-GEOD-43010 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of human centromeric protein A, histone3 K4 and K9 modifications, HP1a and HP1g
Chromatin Immunoprecipitation of centromeric protein A, histone3 K4 and K9 modifications, HP1a and HP1g
ORGANISM(S): Homo sapiens 
2010-02-27 | E-TABM-705 | biostudies-arrayexpress
TranscriptomicsReactivation of ERK signaling causes resistance to EGFR kinase inhibitors (SNP array)
The clinical efficacy of EGFR kinase inhibitors is limited by the development of drug resistance. The irreversible EGFR kinase inhibitor WZ4002 is effective against the most common mechanism of drug resistance mediated by the EGFR T790M mutation. Here we show that in multiple complementary models ha...
ORGANISM(S): Homo sapiens 
2012-10-01 | E-GEOD-37698 | biostudies-arrayexpress
TranscriptomicsMultiple Early Factors Anticipate Post-Acute COVID-19 Sequelae
Post-acute sequelae of COVID-19 (PASC) represent an emerging global crisis. However, quantifiable risk-factors for PASC and their biological associations are poorly resolved. We executed a deep multi-omic, longitudinal investigation of 309 COVID-19 patients from initial diagnosis to convalescence (2...
ORGANISM(S): Homo sapiens 
2022-02-01 | E-MTAB-10129 | biostudies-arrayexpress
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