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TranscriptomicsTranscription profile of hearts extracted from zebrafish embryos treated with SU5402 at 48 hpf
Heart formation requires input from two populations of progenitor cells - the first and second heart fields - that differentiate at distinct times and create different cardiac components. The cardiac outflow tract (OFT) is built through recruitment of late-differentiating, second heart field (SHF) -...
ORGANISM(S): Danio rerio 
2014-05-12 | E-GEOD-55540 | biostudies-arrayexpress
GenomicsComparative RNA-seq analysis between control and SU5402 treated amphioxus (Branchiostoma lanceolatum) embryos
Comparative RNA-seq analysis between control and SU5402 treated amphioxus (Branchiostoma lanceolatum) embryos
PRJNA504393 | ENA
TranscriptomicsComparative RNA-seq analysis between control and SU5402 treated amphioxus (Branchiostoma lanceolatum) embryos
We compared the transcriptomes of Amphioxus (Branchiostoma lanceolatum) control and SU5402 treated embryos to define putative FGF signalling pathway target genes during somitogenesis. Embryos were treated with 50µM of SU5402 from 5.5hpf to 8.5hpf, 11.5hpf, and 14.5hpf or from 15hpf to 18hpf, 21hpf, ...
ORGANISM(S): Branchiostoma lanceolatum 
2020-01-01 | GSE122245 | GEO
TranscriptomicsGallus gallus Control Versus SU5402, LY294002 or U0126 Treated Preingression Epiblast from Gastrula Stage Embryos
Transcriptional profiling of the preingression epiblast versus lateral epiblast, of preingression epiblast from control embryos treated with the DMSO carrier vehicle (0.5%) versus embryos treated with SU5402, U0126 or LY294002. Embryos were stages 5-6 at time of tissue isolation. The preingressi...
ORGANISM(S): Gallus gallus 
2011-02-20 | E-GEOD-27403 | biostudies-arrayexpress
TranscriptomicsCrosstalk between Fgf and Wnt signaling in the zebrafish tailbud
We aimed to expand the knowledge of Fgf and Wnt signaling in the zebrafish tailbud. Both pathways are required for proper axis elongation and segmentation and we wished to explore the genes under the control of each pathway during this process. In addition, we saught to identify crosstalk between th...
ORGANISM(S): Danio rerio 
2012-07-15 | E-GEOD-38969 | biostudies-arrayexpress
TranscriptomicsSW480 Signaling Hub Inhibition
In tumor cells, stepwise oncogenic deregulation of signaling cascades induces alterations of cellular morphology and promotes the acquisition of malignant traits. Using a panel of small molecular inhibitors, we established associated gene expression signatures of key signaling hubs. SW480 cells were...
ORGANISM(S): Homo sapiens 
2011-06-03 | E-GEOD-29689 | biostudies-arrayexpress
TranscriptomicsFGF2-regulated gene expression in cultured mouse spermatogonial stem cells
Transcriptional profiling of mouse spermatogonial stem cells (SSCs) comparing control untreated SSCs with SSCs with exogenous FGF2 withdrawn and FGFR inhibitor SU5402 supplemented (-F+S). Results provide insight into the mechanisms of FGF2-supported in vitro self-renewal of SSCs. Two-condition exper...
ORGANISM(S): Mus musculus 
2010-08-01 | E-GEOD-21294 | biostudies-arrayexpress
TranscriptomicsGallus gallus Control Versus SU5402, LY294002 or U0126 Treated Preingression Epiblast from Gastrula Stage Embryos
Transcriptional profiling of the preingression epiblast versus lateral epiblast, of preingression epiblast from control embryos treated with the DMSO carrier vehicle (0.5%) versus embryos treated with SU5402, U0126 or LY294002. Embryos were stages 5-6 at time of tissue isolation. The preingression e...
ORGANISM(S): Gallus gallus 
2011-02-20 | GSE27403 | GEO
GenomicsGallus gallus
Gallus gallus Control Versus SU5402, LY294002 or U0126 Treated Preingression Epiblast from Gastrula Stage Embryos
PRJNA137265 | ENA
Genomics
Amphiura filiformis raw reads 27hr post fertilization, treated with SU5402
PRJNA345588 | ENA
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