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ProteomicsInteraction of genetic variants activates latent metabolic pathways in yeast
Genetic interactions are fundamental to the architecture of complex traits, yet the molecular mechanisms by which variant combinations influence cellular pathways remain poorly understood. Here, we answer the question of whether interactions between genetic variants can activate unique pathways and ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-07-22 | PXD056947 | Pride
Proteomics Sporulation Yeast Amino acid metabolism Ribosome pathways Single nucleotide polymorphism Transcriptomics 
ModelsThiele2011 - Genome-scale metabolic network of Salmonella Typhimurium (STM_v1_0)
Thiele2011 - Genome-scale metabolic network of Salmonella Typhimurium (STM_v1_0) This model is described in the article: A community effort towards a knowledge-base and mathematical model of the human pathogen Salmonella Typhimurium LT2. Thiele I, Hyduke DR, Steeb B, Fankam ...
2015-07-30 | MODEL1507180017 | BioModels
MetabolomicsInteraction of Genetic Variants Activates Latent Metabolic Pathways in Yeast

Genetic interactions are fundamental to the architecture of complex traits, yet the molecular mechanisms by which variant combinations influence cellular pathways remain poorly understood. Here, we answer the question of whether interactions between genetic variants can activate unique pathways a...

2025-07-22 | MTBLS12761 | MetaboLights
ProteomicsA microbial supply chain for production of anti-cancer drug vinblastine
Monoterpene indole alkaloids (MIAs) are a diverse family of complex plant secondary metabolites with many medicinal properties, including the essential anti-cancer therapeutics vinblastine and vincristine. As MIAs are difficult to chemically synthesize, the world’s supply chain for vinblastine relie...
ORGANISM(S): Saccharomyces Cerevisiae 
2022-09-09 | PXD024976 | panorama
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