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Transcriptional profiling of gene expression of embryonic stem cells from mutant Map3k1 mice in comparison to control EL14 cells. The differential expression of specific genes between the mutant and control groups generated from the microarray will give an idea of the molecular mechanisms regulating...
ORGANISM(S): Mus musculus 
Mapks are regulators of T cell proliferative expansion and cell cycle progression. Genetic analysis of Th17 cells in Map3k1ΔKD and control mice will demonstrate whether Mekk1 (encoded by Map3k1) signaling activates Jnks to regulate cell cycle molecules and proliferative expansion. Comparative tra...
ORGANISM(S): Mus musculus 
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