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MetabolomicsNiacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Cell NAMPTi treatment)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7251 | MetaboLights
ProteomicsMALDI spectra of Cutibacterium and Staphylococcus species
MALDI spectra of Cutibacterium and Staphylococcus species
ORGANISM(S): Cellular Organisms 
2021-06-07 | PXD025627 | JPOST Repository
TranscriptomicsNon-neuronal acetylcholine as an endogenous regulator of proliferation and differentiation of Lgr5-positive stem cells in mice
Acetylcholine (ACh) has been considered a neurotransmitter residing in central, parasympathetic and neuromuscular synapses of mammals. Here, experiments using crypt-villus organoids that lack nerve and immune cells in culture led us to suggest that endogenous ACh is synthesized in the intestinal epi...
ORGANISM(S): Mus musculus 
2013-08-15 | E-GEOD-49864 | biostudies-arrayexpress
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