Sugiura Kenta K

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Metabolomics (3)
Proteomics (2)

Organisms

Caenorhabditis elegans (2)

Repository

MetaboLights (3)
jPOST (2)

Technology Type

Mass spectrometry (3)

Instrument Platform

Capillary electrophoresis MS - negative (3)
Capillary electrophoresis MS - positive (3)

Publication Date

2023 (3)
2026 (2)

CHEBI ID

CHEBI:10049 (3)
CHEBI:10072 (3)
CHEBI:1026 (3)
CHEBI:1148 (3)
CHEBI:1157 (3)
CHEBI:132546 (3)
CHEBI:132958 (3)
CHEBI:134206 (3)
CHEBI:135063 (3)
CHEBI:139328 (3)
CHEBI:14314 (3)
CHEBI:143269 (3)
CHEBI:14336 (3)
CHEBI:1456 (3)
CHEBI:14973 (3)
CHEBI:15318 (3)
CHEBI:15346 (3)
CHEBI:15351 (3)
CHEBI:15354 (3)
CHEBI:15355 (3)
CHEBI:15356 (3)
CHEBI:15380 (3)
CHEBI:15422 (3)
CHEBI:15428 (3)
CHEBI:1547 (3)
CHEBI:15479 (3)
CHEBI:15531 (3)
CHEBI:15551 (3)
CHEBI:15553 (3)
CHEBI:15573 (3)

Metabolite Name

(Methylthio)acetate (2)
1-Aminoethylphosphonate (2)
10-Hydroxydecanoate (2)
2',3'-cCMP (2)
2,3-DPG (2,3-Disphospho-D-glycerate) (2)
2,3-Pyridinedicarboxylate (2)
2,4-Dihydroxypyrimidine-5-carboxylate (2)
2,5-Dihydroxybenzoate (2)
2-Amino-3-phosphonopropionate (2)
2-Aminoethylphosphonate (2)
2-Deoxyglucose 6-phosphate (2)
2-Deoxyribose 1-phosphate (2)
2-Furoate (2)
2-Hydroxy-4-methylpentanoate (2)
2-Hydroxybutyrate (2)
2-Hydroxyglutarate (2)
2-Hydroxyisobutyrate (2)
2-Hydroxyoctanoate (2)
2-Hydroxypentanoate (2)
2-Hydroxyphenylacetate (2)
2-Isopropylmalate (2)
2-Oxoadipate (2)
2-Oxobutyrate (2)
2-Oxoglutarate (2)
2-Oxoisopentanoate (2)
2-Oxooctanoate (2)
2-Quinolinecarboxylate (2)
2-Thiopheneacetate (2)
2PG (D-Glycerate 2-phosphate) (2)
3',5'-Cyclic dAMP (2)

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Niacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Cell NAMPTi treatment)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7251 | MetaboLights

Niacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Mouse NAMPT targeted therapy)

2023-10-10 | MTBLS7252 | MetaboLights

Niacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Mouse NAD targeted time-course)

2023-10-10 | MTBLS7253 | MetaboLights

TMTpro-16plex analysis of worm embryos with unc-32 RNAi

An rrf-1(pk1417) mutant strain was used to knockdown unc-32 gene function specifically in the germline, in which somatic RNAi, but not germline RNAi, was significantly repressed. Gravid adult hermaphrodites were collected in M9 buffer and bleached to obtain hard-shelled embryos. The embryos were was...

ORGANISM(S): Caenorhabditis Elegans

2026-04-09 | PXD065081 | JPOST Repository

DIA of GFP-Trap IP from worms expressing ROOM1/2-GFP

Worms containing the transgene room-1::FLAG::GFP or room-2::FLAG::GFP were used for the Co-IP MS experiments. Approximately 25,000 gravid adult hermaphrodites were collected and homogenized in HBS buffer (20 mM HEPES-NaOH pH7.5, 150 mM NaCl, 1 mM MgCl2, and 1 mM EDTA with Complete Ultra Tablet Mini,...