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Analysis of gene expression changes in response to TTV-tth8 miRNA Total RNA harvested 30 hours after transfection of HEK293TT cells with recircularized TTV-tth8 genome, miRNA mutant TTV-tth8 genome, SV40 miRNA recombinant TTV-tth8 genome, or pUC vector using Lipofectamine 2000.
ORGANISM(S): Homo sapiens 
The purpose of this study was to identify transcripts differentially expressed in zebrafish embryos exposed to two oxygenated PAHs, 1,9-benz-10-anthrone and benzanthracene-7,12-dione, which cause abnormal development. We used RNA-seq (Illumina HiSeq) to identify mRNA profiles of whole zebrafish embr...
ORGANISM(S): Danio rerio 
The product of the Bmal1 locus is an essential component of the circadian clock that plays important roles in various aspects of reproductive biology,and when disrupted results in infertility. In an effort to establish the identity of the tissue specific clock that is responsible for this infertilit...
ORGANISM(S): Mus musculus 
Deep sequencing of small RNAs from three Phytophthora species, P. infestans, P. ramorum and P. sojae, was done to systematically analyze small RNA-generating components of Phytophthora genomes. We found that each species produces two distinct small RNA populations that are predominantly 21- or 25-nu...
ORGANISM(S): Phytophthora infestans 

Cannabis and stimulants are among the most widely used illicit drug in the United States, and their use is associated with substantial physical and psychiatric sequelae. Twin studies have shown a substantial genetic component to the etiology of cannabis and stimulant use disorders, but, genome-wi...

RNA-Sequencing is a transformative method that captures the quantitative dynamics of a transcriptome with exquisite sensitivity and single-base resolution. There are, however, few computational pipelines for RNA-Seq with statistical tests that evince sufficient robustness and power as demanded by th...
ORGANISM(S): Arabidopsis thaliana 

The Epi4K project began in 2011 as an international, multi-center study that seeks to identify and characterize the genetic bases of complex epilepsies. The Center without Walls Epi4K project includes three cores and four scientific projects, as well as a steering committee comprised of the prima...

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