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TranscriptomicsExpression profiling of the TC32 Ewing sarcoma cell line following silencing of SUPT6H, SF3B1 or HNRNPH1
The investigation of the function of SUPT6H, SF3B1 and HNRNPH1 in Ewing sarcoma The expression profiles of TC32 Ewing sarcoma cells were determine 48 hours post siRNA-transfected. Groups consisted of untreated cells (three samples), and negative control (siNeg) transfected-TC32 cells (six samples), ...
ORGANISM(S): Homo sapiens 
2016-01-15 | E-GEOD-67736 | biostudies-arrayexpress
TranscriptomicsExpression profiling of the TC32 Ewing sarcoma cell line following silencing of SUPT6H, SF3B1 or HNRNPH1
The investigation of the function of SUPT6H, SF3B1 and HNRNPH1 in Ewing sarcoma
ORGANISM(S): Homo sapiens 
2016-01-15 | GSE67736 | GEO
GenomicsHomo sapiens
Expression profiling of the TC32 Ewing sarcoma cell line following silencing of SUPT6H, SF3B1 or HNRNPH1
PRJNA280833 | ENA
TranscriptomicsSpt6 regulates intragenic and antisense transcription, nucleosome positioning, and histone modifications genome-wide in fission yeast [RNA-seq]
Spt6 is a highly conserved histone chaperone that interacts directly with both RNA polymerase II and histones to regulate gene expression. To gain a comprehensive understanding of the requirements for this critical factor, we have performed genome-wide analyses of transcription, chromatin structure...
ORGANISM(S): Schizosaccharomyces pombe 
2013-10-09 | E-GEOD-49573 | biostudies-arrayexpress
TranscriptomicsSPT6-driven error-free DNA repair safeguards genomic stability of glioblastoma cancer stem-like cells
Knockdown of SUPT6H (aka Spt6) using siRNA against Spt6 compared to treatement with scrambled CTRL siRNA in patient derived glioblastoma cell line
ORGANISM(S): Homo sapiens 
2020-07-17 | GSE125621 | GEO
TranscriptomicsTranscription profiling of yeast with a C-terminal deletion of the RNA polymerase II elongation factor Spt6 or overexpression of Spt6
Influence of a C-terminal deletion of the RNA polymerase II elongation factor Spt6 on the transcription of the yeast genome. In parallel the influence of a Spt6 overexpression on gene expression is analyzed.
ORGANISM(S): Saccharomyces cerevisiae 
2009-04-08 | E-MEXP-2123 | biostudies-arrayexpress
GenomicsSpt6 regulates intragenic and antisense transcription, nucleosome positioning, and histone modifications genome-wide in fission yeast [Mnase-seq]
Spt6 is a highly conserved histone chaperone that interacts directly with both RNA polymerase II and histones to regulate gene expression. To gain a comprehensive understanding of the requirements for this critical factor, we have performed genome-wide analyses of transcription, chromatin structure...
ORGANISM(S): Schizosaccharomyces pombe 
2013-10-09 | E-GEOD-49572 | biostudies-arrayexpress
TranscriptomicsshRNA RNA-seq from HepG2 (ENCSR281KCL)
RNA-seq on HepG2 cells treated with an shRNA knockdown against SUPT6H. (SUPT6H_BGHLV30) For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf
ORGANISM(S): Homo sapiens 
2016-11-08 | GSE88160 | GEO
TranscriptomicsshRNA RNA-seq from K562 (ENCSR530BOP)
RNA-seq on K562 cells treated with an shRNA knockdown against SUPT6H. (SUPT6H_BGKLV28) For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf
ORGANISM(S): Homo sapiens 
2016-11-08 | GSE88338 | GEO
TranscriptomicsSpt6 Levels are Modulated by PAAF1 and 26S Proteasome to Regulate the HIV-1 LTR and a Subset of Cellular Genes involved in Cancer.
Effect of PAAF1 and Spt6 knock-down on gene expression. Total RNAs were extracted from HeLa-LTR-Luc cells in which PAAF1 or Spt6 had been knock down by a specific siRNA or HeLa-LTR-Luc cells that had been transfected with a control siRNA (“si Neg”). Differentially expressed genes in PAAF1 knock-down...
ORGANISM(S): Homo sapiens 
2012-05-28 | E-GEOD-32033 | biostudies-arrayexpress
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