Sort   by:  
 Page size 
ProteomicsMass spectrometry based identification of similarities and differences in protein content of cutaneous melanoma cell lines and exosomes
Intercellular transport of proteins mediated by extracellular vesicles (EVs) exosomes and ectosomes, is one of the factors facilitating carcinogenesis. Therefore, the research on protein cargo of melanoma-derived EVs may provide a better understanding of mechanisms related to melanoma progression an...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-12-15 | MSV000090907 | MassIVE
ProteomicsShotgun proteomics of thyroid carcinoma exosomes: insight into the role of exosomal proteins in carcinogenesis and thyroid homeostasis
The transport of molecules via exosomes is one of the factors involved in cancer development, and transferred molecules can serve as specific tumor biomarkers. The aim of the study was the LC MS/MS proteomic analysis of exosomes released by FTC and 8305C thyroid cancer cell lines, and reference Nthy...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-10-19 | MSV000093152 | MassIVE
ProteomicsMGAT3 and MGAT5 overexpression alters the protein cargo of extracellular vesicles released by metastatic melanoma cells
Extracellular vesicles (EVs) are potential non-invasive diagnostic, prognostic, and therapeutic tools. Additionally, they are important contributors to tumorigenesis. Glycosylation has been found to modulate the composition of the EV proteome, and increased amounts of beta 1,6-branched N-glycans, sy...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-11-08 | MSV000096340 | MassIVE
ProteomicsComparative proteomic profiling of ectosomes derived from thyroid carcinoma and normal thyroid cells uncovers multiple proteins with functional implications in cancer
Proteins carried by tumor-derived ectosomes play an important role in cancer progression and are considered promising diagnostic markers. In the present study a shotgun nanoLC-MS/MS proteomic approach was applied to profile and compare the protein content of ectosomes released in vitro by normal hum...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-02-17 | MSV000088850 | MassIVE
ProteomicsProteomic profiling of ectosomes derived from paired urothelial bladder cancer and normal cells reveals the presence of biologically-relevant molecules
Protein content of extracellular vesicles (EVs) can modulate different processes during carcinogenesis. Novel proteomic strategies have been applied several times to profile proteins present in exosomes released by urothelial bladder cancer (UBC) cells. However, similar studies have not been conduct...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-05-06 | MSV000087370 | MassIVE
ProteomicsMass spectrometry-based proteomic characterization of cutaneous melanoma ectosomes reveals the presence of cancer-related molecules
Cutaneous melanoma (CM) is an aggressive type of skin cancer for which effective biomarkers are still needed. Due to the development of protocols for their successful isolation, protein content of extracellular vesicles (EVs) (including ectosomes and exosomes) became increasingly investigated in ter...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-02-03 | MSV000084892 | MassIVE
Sort   by:  
 Page size