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GenomicsSP1/2/3 and NfY cooccurency in MEFs
Investigation of the binding behaviour of Sp1, Sp2, Sp3 and NF-ya, NF-yb and NF-yc in mouse embryonic fibroblasts and of Sp1, Sp2 and Sp3 in HEK-293 cells reveals distinct binding of the seemingly similar transcription factors Sp1/3 and Sp2.
ORGANISM(S): Mus musculus 
2015-01-30 | E-MTAB-2970 | biostudies-arrayexpress
TranscriptomicsGenome-wide Analysis of Sp2 Occupancy and Expression Profiling Establish Sp2 as a Sequence-specific Transcription Factor Regulating Fundamental Cellular Processes - Expression Profiling
Mouse embyronic fibroblasts (MEFs) were depleted for transcription factor Specificity Factor 2 (Sp2) via Cre-Recombinase, harvested either 7 days or several weeks post infection and their expression profile compared to mock-infected MEFs.
ORGANISM(S): Mus musculus 
2012-05-24 | E-MTAB-1015 | biostudies-arrayexpress
GenomicsGenome-wide Analysis of Sp2 Occupancy and Expression Profiling Establish Sp2 as a Sequence-specific Transcription Factor Regulating Fundamental Cellular Processes - ChIPseq
Genome-wide Analysis of Sp2 Occupancy and Expression Profiling Establish Sp2 as a Sequence-specific Transcription Factor Regulating Fundamental Cellular Processes - ChIPseq
ORGANISM(S): Homo sapiens 
2012-05-24 | E-MTAB-994 | biostudies-arrayexpress
GenomicsL3MBTL2 in HEK293 cells - ChIPseq
To elucidate the (possibly sumo dependent) binding sites of L3MBTL2, wild type L3MBTL2, L3MBTL2-Flag and L3MBTL2-KR-Flag ChIPs from HEK293 cells were analyzed via ChIPseq
ORGANISM(S): Homo sapiens 
2014-01-14 | E-MTAB-1731 | biostudies-arrayexpress
GenomicsChIP-seq of Pbx1, Prep1 and Sp2 in WT MEFs, Sp2ko MEFs and in Sp2ko MEFs ectopically expressing Flag-tagged full length Sp2; and ChIPexo of Sp2 in WT and Sp2ko MEFs
We investigated the genomic binding profiles of the transcription factors Pbx1, Prep1, and Sp2 in mouse embryonic fibroblasts using ChIPseq and ChIPexo. Refer to E-MTAB-2970 and E-MTAB-994 for KO and IgG Controls.
ORGANISM(S): Mus musculus 
2018-10-17 | E-MTAB-7125 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse heart from E12.5 wildtype- and Sp3 animals
Mice lacking the zinc finger transcription factor Specificity protein 3 (Sp3) die prenatally in the C57Bl/6 background. To elucidate the cause of mortality we analyzed the potential role of Sp3 in embryonic heart development. Sp3 null hearts display defective looping at E10.5, and at E14.5 the Sp3 n...
ORGANISM(S): Mus musculus 
2008-06-17 | E-GEOD-9124 | biostudies-arrayexpress
TranscriptomicsPRC1.6 RNAseq
MGA was depleted via Crisper/Cas9 in HEK293 cells and the resulting gene expression changes were profiled.
ORGANISM(S): Homo sapiens 
2018-01-24 | E-MTAB-6005 | biostudies-arrayexpress
GenomicsPRC1.6 ChIPseq - HEK239
Components of the PRC1.6 complex were depleted via Crisper/Cas9 and ChIPed in HEK293 cells.
ORGANISM(S): Homo sapiens 
2018-01-24 | E-MTAB-6006 | biostudies-arrayexpress
GenomicsPRC1.6 ChIPseq - mouse ES
Components of the PRC1.6 complex were depleted via Crisper/Cas9 and ChIPed in mouse ES cells.
ORGANISM(S): Mus musculus 
2018-01-24 | E-MTAB-6007 | biostudies-arrayexpress
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