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TranscriptomicsExpression data from Balb/c mice kidney samples
Males are 50% more likely to develop end stage kidney failure compared to women. As a model of the human condition we analyzed gene expression changes in healthy and diseased mouse kidneys. Interestingly, the set of gender biased genes in healthy kidneys were different from those in diseased kidneys...
ORGANISM(S): Mus musculus 
2010-03-03 | E-GEOD-12683 | biostudies-arrayexpress
TranscriptomicsExpression data from Human Kidney (HK) samples
Males are 50% more likely to develop end stage kidney failure compared to women. In this study we wanted to find out the molecular mechanism responsible for this increased risk. We collected kidney samples from patients with and without kidney disease and performed a comprehensive gene expression an...
ORGANISM(S): Homo sapiens 
2010-04-13 | E-GEOD-12682 | biostudies-arrayexpress
TranscriptomicsTranscriptome Analysis of Human Diabetic Kidney Disease (DKD Glomeruli vs. Control Glomeruli)
We identified 1,700 differentially expressed probesets in DKD glomeruli and 1,831 in diabetic tubuli; 330 probesets were commonly differentially expressed in both compartments. The canonical complement signaling pathway was determined to be statistically differentially regulated in both DKD glomerul...
ORGANISM(S): Homo sapiens 
2011-08-02 | E-GEOD-30528 | biostudies-arrayexpress
TranscriptomicsTranscriptome Analysis of Human Diabetic Kidney Disease (DKD Tubuli vs. Control Tubuli)
We identified 1,700 differentially expressed probesets in DKD glomeruli and 1,831 in diabetic tubuli; 330 probesets were commonly differentially expressed in both compartments. The canonical complement signaling pathway was determined to be statistically differentially regulated in both DKD glomerul...
ORGANISM(S): Homo sapiens 
2011-08-02 | E-GEOD-30529 | biostudies-arrayexpress
TranscriptomicsTranscriptome Analysis of Human Diabetic Kidney Disease
This SuperSeries is composed of the following subset Series: GSE30528: Transcriptome Analysis of Human Diabetic Kidney Disease (DKD Glomeruli vs. Control Glomeruli) GSE30529: Transcriptome Analysis of Human Diabetic Kidney Disease (DKD Tubuli vs. Control Tubuli) GSE30566: Transcriptome Analysis of H...
ORGANISM(S): Homo sapiens 
2011-08-02 | E-GEOD-30122 | biostudies-arrayexpress
TranscriptomicsTranscriptome Analysis of Human Diabetic Kidney Disease (Control Glomeruli vs. Control Tubuli)
We identified 1,700 differentially expressed probesets in DKD glomeruli and 1,831 in diabetic tubuli; 330 probesets were commonly differentially expressed in both compartments. The canonical complement signaling pathway was determined to be statistically differentially regulated in both DKD glomerul...
ORGANISM(S): Homo sapiens 
2011-08-02 | E-GEOD-30566 | biostudies-arrayexpress
GenomicsHistone tail modification profiles of human renal tubule epithelial cells
To annotate the regulatory elements in the renal tubule epithelial cells, we profiled 6 histone ChIP-seq in the human kidney epithelical cells (HKC8). We pulled down the DNA with specific antibodies of interests against histone tail modifications in the human rebal tubule epithelial cells. The resul...
ORGANISM(S): Homo sapiens 
2013-08-09 | E-GEOD-49637 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of Chronic kidney disease
Epidemiological studies indicate that adverse intrauterine and postnatal environment has a long-lasting role in chronic kidney disease (CKD) development. Epigenetic information can represent a plausible carrier for mediating this programming effect. Here we demonstrate that genome-wide cytosine meth...
ORGANISM(S): Homo sapiens 
2013-07-18 | E-GEOD-48944 | biostudies-arrayexpress
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