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TranscriptomicsToxoplasma gondii arginine methyltransferase 1 (PRMT1) regulates parasite counting during tachyzoite cell division
PRMT1 is thought to be responsible for the majority of PRMT activity in Toxoplasma gondii, but its exact function is unknown. We generated T. gondii mutants lacking PRMT1 (∆prmt1) by deletion of the PRMT1 gene. ∆prmt1 parasites exhibit morphological defects during cell division and grow slowly, and ...
ORGANISM(S): Toxoplasma gondii 
2015-09-18 | E-GEOD-73177 | biostudies-arrayexpress
TranscriptomicsA nucleolar AAA-NTPase is required for Toxoplasma gondii division
Toxoplasma gondii cell cycle mutant 11-104A4 reversibly arrests in the G1 phase. The defect in this mutant was mapped by genetic complementation to a gene encoding a novel AAA-ATPase/CDC48 family member (TgNoAP1). A change in a tyrosine to a cysteine upstream of an AAA+ domain leads to protein ins...
ORGANISM(S): Toxoplasma gondii 
2013-01-27 | E-GEOD-43784 | biostudies-arrayexpress
TranscriptomicsDiscovery of a splicing regulator required for cell cycle progression
Toxoplasma gondii temperature sensitive mutant 12-109C6 conditionally arrests in the G1 phase due to a single point mutation in a novel protein containing a single RNA-recognition-motif (TgRRM1). The resulting tyrosine to asparagine amino acid change in TgRRM1 causes severe temperature instability ...
ORGANISM(S): Toxoplasma gondii 
2013-01-08 | E-GEOD-43315 | biostudies-arrayexpress
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