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MetabolomicsEndoplasmic reticulum-derived bodies enable a single-cell chemical defense in Brassicaceae plants
Brassicaceae plants have a dual-cell type of chemical defense against herbivory. Here we show a novel single-cell defense involving endoplasmic reticulum (ER)-derived organelles (ER bodies) and the vacuoles. We identify various glucosinolates as endogenous substrates of the ER-body β-glucosidases BG...
2020-02-04 | MTBLS1383 | MetaboLights
TranscriptomicsRIP-seq of livers in C57BL/6J mice with antibodies against Cnot3, Ago2, and BRF1
Shortening of polyadenosine (poly(A)) tails (deadenylation) is the initial step in the decay of most mRNAs. The CCR4-NOT complex is the major deadenylase in mammals. Interaction of Cnot1 with RNA binding proteins, including the miRNA-induced silencing complex (miRISC), which includes Argonaute (Ago)...
ORGANISM(S): Mus musculus 
2020-03-30 | E-MTAB-6941 | biostudies-arrayexpress
TranscriptomicsRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Gene expression is balanced by transcription and mRNA degradation. Shortening of polyadenosine (poly(A)) tails (deadenylation) is the initial step in the decay of most mRNAs. However, the mechanism by which deadenylation controls mRNA expression is not fully understood. This experiment aimed to dete...
ORGANISM(S): Mus musculus 
2020-03-30 | E-MTAB-5901 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of primary mouse embryonic palatal mesenchymal cells in Tgfbr2 mutant mouse models
The overall goal of this project is to investigate the role of TGF-beta signaling in regulating the cellular metabolism of cranial neural crest (CNC) cells during palate development. Here, we conducted gene expression profiling of primary mouse embryonic palatal mesenchymal (MEPM) cells from wild ty...
ORGANISM(S): Mus musculus 
2013-10-01 | E-GEOD-46150 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of the tongue in Tgfbr2 mutant mouse models
The overall goal of this project is to investigate the role of TGF-beta signaling in tongue development in order to study the contribution of cranial neural crest (CNC) cells towards the patterning of cranial mesoderm for proper tongue formation. Here, we conducted gene expression profiling of embry...
ORGANISM(S): Mus musculus 
2013-04-11 | E-GEOD-45968 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of anterior and posterior palatal tissue from Tgfbr2 mutant mouse models
The overall goal of this project is to investigate the role of TGF-beta signaling in epithelial cells as it pertains to the orientation of muscle fibers in the soft palate during embryogenesis. Here, we first conducted gene expression profiling of the anterior and posterior portions of the palate fr...
ORGANISM(S): Mus musculus 
2013-10-01 | E-GEOD-46211 | biostudies-arrayexpress
UnknownIntensive endoscopic resection for downstaging of polyp burden in patients with familial adenomatous polyposis (J-FAPP Study III): a multicenter prospective interventional study.
Not available
S-EPMC10060053 | biostudies-literature
ProteomicsHER2 RIME experiment from breast cancer specimen
RIME targeting ERBB2 (HER2) proteins was performed to analyse ERBB2 interactome to screen novel breast cancer diagnostic markers.
ORGANISM(S): Homo Sapiens (human) 
2025-09-09 | PXD061456 | JPOST Repository
ProteomicsHER2 RIME experiment from SK-BR-3
RIME targeting ERBB2 (HER2) proteins was performed to compare ERBB2 immunoprecipitation efficiency and the quality of the interactome.
ORGANISM(S): Homo Sapiens (human) 
2025-09-09 | PXD058365 | JPOST Repository
ProteomicsHER2 RIME experiment from breast cancer specimen 2
RIME targeting ERBB2 (HER2) proteins was performed to analyse ERBB2 interactome to screen novel breast cancer diagnostic markers.
ORGANISM(S): Homo Sapiens (human) 
2025-09-09 | PXD066103 | JPOST Repository
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