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TranscriptomicsLARP1 mRNP scaffolds mTORC1 to stimulate translation initiation of an essential class of mRNAs
The RNA biding protein, LARP1, has been proposed to function downstream of mTORC1 to positively regulate the translation of 5M-bM-^@M-^YTOP mRNAs such as ribosome protein (RP) mRNAs. However, its regulatory roles in mTORC1-mediated translation remain unclear. PAR-CLIP of LARP1 revealed its direct an...
ORGANISM(S): Homo sapiens 
2014-07-31 | E-GEOD-59599 | biostudies-arrayexpress
TranscriptomicsSingle cell RNA sequencing of iPSC and Human dermal fibroblasts
single cell RNA sequencing of iPSC and Human dermal fibroblasts using 10x Genomics with 3-prime, 5-prime poly(dT) primer, and 5-prime random primer. For comparison in gene, ncRNA and enhancer detection.
ORGANISM(S): Homo sapiens 
2021-05-13 | E-MTAB-10385 | biostudies-arrayexpress
TranscriptomicsSingle cell ATAC-seq of human peripheral blood mononuclear cells under resting and stimulated conditions
Single cell ATAC-seq of PBMC - resting and stimulated. Used for comparison to asses the capabilies of the five-prime sequencing method in the detection of cis-regulatory elements using SCAFE (see publication).
ORGANISM(S): Homo sapiens 
2021-04-13 | E-MTAB-10382 | biostudies-arrayexpress
TranscriptomicsATAC-seq of iPSC and human dermal fibroblasts
ATAC-seq of iPSC and human dermal fibroblasts, used to compare open chromatin and transcription signal.
ORGANISM(S): Homo sapiens 
2021-05-02 | E-MTAB-10381 | biostudies-arrayexpress
TranscriptomicsCAGE sequencing of iPSC and Human dermal fibroblasts
CAGE sequencing of iPSC and Human dermal fibroblasts, total RNA and fractionated into nuclear, cytoplasmic and chromatin fractions.
ORGANISM(S): Homo sapiens 
2021-04-28 | E-MTAB-10384 | biostudies-arrayexpress
TranscriptomicsSingle cell five-prime end sequencing of PBMC - resting and stimulated
Single cell five-prime end sequencing of PBMC - resting and stimulated. Used to asses the five-prime sequencing method in the detection of cis-regulatory elements using SCAFE (see publication)
ORGANISM(S): Homo sapiens 
2021-04-28 | E-MTAB-10378 | biostudies-arrayexpress
TranscriptomicsRNA sequencing of iPSC and Human dermal fibroblasts
RNA sequencing of iPSC and Human dermal fibroblasts, total RNA and fractionated into nuclear, cytoplasmic and chromatin fractions.
ORGANISM(S): Homo sapiens 
2021-04-28 | E-MTAB-10383 | biostudies-arrayexpress
ProteomicsProximity-dependent biotinylation reveals an interaction between ubiquitin-specific peptidase 46 and centrosome-related proteins
To characterize the protein interaction network of USP46, BioID analysis was conducted on a knock-in cell line that expresses USP46 and biotin ligase fusion protein stably.
ORGANISM(S): Mus Musculus (mouse) 
2025-03-25 | PXD053674 | JPOST Repository
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