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TranscriptomicsmiRNA profiling of CD4+ T cells in chronically infected HIV-1 patients, LTNPs and healthy controls
We extracted total RNA from CD4+ T cells from 3 patient groups: chronic HIV-1 patients (CHI), long term non-progressors (LTNPs) and healthy controls (HC). Array results show that a large number of miRNAs are altered in HIV-1 infected patients compared to HC. Most of the differentially expressed mi...
ORGANISM(S): Homo sapiens 
2012-05-21 | E-GEOD-24022 | biostudies-arrayexpress
TranscriptomicsInterleukin-27 is a potent inhibitor of cis HIV-1 replication in Monocyte-derived Dendritic Cells via a Type I Interferon-independent pathway
IL-27 treated DCs were shown to be highly potent inhibitors of cis HIV-1, particularly of CCR5 tropic strains. Microarray studies of IL-27 treated DCs showed no up-regulation of Type I (IFN) gene expression. Neutralization of the Type-I IFN receptor had no impact on the HIV inhibition. Lastly, IL-27...
ORGANISM(S): Homo sapiens 
2013-03-29 | E-GEOD-44732 | biostudies-arrayexpress
UnknownChild and Adolescent Health From 1990 to 2015: Findings From the Global Burden of Diseases, Injuries, and Risk Factors 2015 Study.
Not available
S-EPMC5540012 | biostudies-literature
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