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The objective of this project was to identify changes in protein expression in R. intestinalis and P. merdae as a response to the treatment with the antidepressant duloxetine, the sweetener isosteviol and a combination of both. 18 samples before and after treatment were collected for each of the two...
ORGANISM(S): Parabacteroides merdae Roseburia intestinalis 
2026-04-30 | PXD045140 | Pride

The gut microbiota is implicated in adverse effects associated with low-calorie sweeteners. Yet, the direct impact of sweeteners on gut bacteria has not been systematically assessed. Here we report interactions between 25 phylogenetically diverse gut bacterial strains and 39 commercially used swe...

2025-06-11 | MTBLS11480 | MetaboLights
Chemical-genetic pooled screen of barcoded transposon mutant library of Parabacteroides merdae under isosteviol, duloxetine and combination.
Modulation of gut bacterial metabolism by commonly consumed sweeteners
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