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TranscriptomicsTranscription profiling of lung tissue of male Sprague Dawley rats after exposure to saline, isopropyl alcohol and sulfur mustard for 30 min, 1 hr, 3 hr, 6 hr, or 24 hr
Male Sprague-Dawley rats were exposed to saline, isopropyl alcohol, 1mg/kg, 3mg/kg or 6 mg/kg sulfur mustard for 30 min, 1 hr, 3 hr, 6 hr, or 24 hr before analysis of lung tissue by oligonucleotide array analysis.
ORGANISM(S): Rattus norvegicus 
2007-09-14 | E-GEOD-1888 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse ears exposed to sulfur mustard alone, sulfur mustard preceded by drug treatment, or vehicle compounds to identify gene expression changes that correlate with compound efficacy
Sulfur mustard (SM) is a potent alkylating agent. We are developing medical countermeasures to reduce the injury caused by SM exposure. Screening in the mouse ear vesicant model has identified three effective compounds: dimercaprol (British anti-lewisite), indomethacin, and octyl homovanillamide (OH...
ORGANISM(S): Mus musculus 
2007-12-01 | E-GEOD-2950 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human growth plate chondrocytes were isolated from the distal femoral growth plate from 3 different adolescents undergoing epiphysiodesis
Human growth plate chondrocytes were isolated from the distal femoral growth plate from 3 different adolescents undergoing epiphysiodesis. Cell were isolated and grown in monolayers, long term, in 20% serum. Cells were replated and cultured 48 h in 0.5% serum.
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-1278 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human growth plate chrondrocytes grown in monolayer, 0.5 vs. 20% serum
Human growth plate chondrocytes were isolated from the distal femoral growth plate from a single adolescent undergoing epiphysiodesis. Cell were isolated and grown in monolayers, long term. Cells were replated and cultured in 0.5% or 20% serum.
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-1277 | biostudies-arrayexpress
UnknownSurvival Outcomes Associated With Clinical and Pathological Response Following Neoadjuvant FOLFIRINOX or Gemcitabine/Nab-Paclitaxel Chemotherapy in Resected Pancreatic Cancer.
Not available
S-EPMC9634701 | biostudies-literature
UnknownEfficacy of checkpoint inhibition after CAR-T failure in aggressive B-cell lymphomas: outcomes from 15 US institutions.
Not available
S-EPMC10425681 | biostudies-literature
UnknownInterferon alfa-2a versus combination therapy with interferon alfa-2a, interleukin-2, and fluorouracil in patients with untreated metastatic renal cell carcinoma (MRC RE04/EORTC GU 30012): an open-label randomised trial.
Not available
S-EPMC2835851 | biostudies-literature
UnknownCorrection to: Randomized phase 2 trial of pevonedistat plus azacitidine versus azacitidine for higher-risk MDS/CMML or low-blast AML.
Not available
S-EPMC9119221 | biostudies-literature
UnknownRandomized phase 2 trial of pevonedistat plus azacitidine versus azacitidine for higher-risk MDS/CMML or low-blast AML.
Not available
S-EPMC8257476 | biostudies-literature
UnknownA Clinical Phase 1B Study of the CD3xCD123 Bispecific Antibody APVO436 in Patients with Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome.
Not available
S-EPMC8394899 | biostudies-literature
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