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TranscriptomicsInfluence of 17M-NM-2-estradiol on Gene Expression of Paracoccidioides During Mycelia-to-Yeast Transition
Background: Paracoccidioides is the causative agent of paracoccidioidomycosis, a systemic mycosis endemic to Latin America. Infection is initiated by inhalation of conidia (C) or mycelial (M) fragments, which subsequently differentiate into yeast (Y). Epidemiological studies show a striking predomin...
ORGANISM(S): Paracoccidioides brasiliensis Pb01 
2011-12-14 | E-GEOD-30466 | biostudies-arrayexpress
TranscriptomicsInteractions of cytokines in peripheral blood cells from Systemic Lupus Erythematosus
SLE patients are always with various disease manifestation. Various cytokines are pointed interacting and playing pathological roles in SLE although the etiopathology is still obscure. In this study, we aimed to investigate the effects of cytokine interactions in the immune response of SLE patients....
ORGANISM(S): Homo sapiens 
2009-05-31 | E-GEOD-12374 | biostudies-arrayexpress
MetabolomicsSystemic metabolite changes due to PHD inhibition
Not available
ORGANISM(S): Mus musculus 
ST001866 | MetabolomicsWorkbench
TranscriptomicsTranscription profiling of human MCF-7 cells treated with proteasome inhibitor MG132 and either dexamethasone or 17b-estradiol
The objective of the study was to investigate the effect of proteasome inhibition on glucocorticoid and estrogen receptor regulated gene expression. Experiment Overall Design: MCF-7 cells were treated with proteasome inhibitor (MG132), dexamethasone, 17b-estradiol or MG132 plus dexamethasone or MG13...
ORGANISM(S): Homo sapiens 
2008-06-20 | E-GEOD-8383 | biostudies-arrayexpress
TranscriptomicsExpression data from MCF-7 cells transfected with miR-26a and treated or not with estradiol
Altered expression of microRNAs (miRNAs), an abundant class of small non-protein-coding RNAs that mostly function as negative regulators of protein-coding gene expression, is common in cancer. Here we analyze the regulation of miRNA expression in response to estrogen, a steroid hormone that is invol...
ORGANISM(S): Homo sapiens 
2009-08-04 | E-GEOD-17460 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat peripheral blood leukocytes treated with the estrogen receptor agonists estradiol, PPT and DPN to investigates the functional roles of estrogen receptor alpha and beta
This experiment investigates the functional roles of estrogen receptor alpha and beta in peripheral blood leukocytes by using selective estrogen receptor agonists. The agonists that are used are estradiol (E2), the selective ER-alpha agonist PPT (4,4',4''-(4-Propyl-[1H]-pyrazole-1,3,5-triyl)trisphen...
ORGANISM(S): Rattus norvegicus 
2007-05-30 | E-TABM-269 | biostudies-arrayexpress
UnknownTX-004HR vaginal estradiol has negligible to very low systemic absorption of estradiol.
Not available
S-EPMC5404400 | biostudies-literature
TranscriptomicsAorta- and liver-specific ERalpha binding patterns and gene regulation by estrogen
Estrogen has vascular protective effects in premenopausal women and in women under 60 receiving hormone replacement therapy. However, estrogen also increases risks of breast and uterine cancers and of venous thromboses linked to upregulation of coagulation factors in the liver. In mouse models, the ...
ORGANISM(S): Mus musculus 
2014-06-30 | E-GEOD-57804 | biostudies-arrayexpress
GenomicsMicrobial Resilience and Functional Gene Adaptation to Acute Estradiol Surges
Microbial Resilience and Functional Gene Adaptation to Acute Estradiol Surges
PRJEB101296 | ENA
Unknown17-β Estradiol reduces atherosclerosis without exacerbating lupus in ovariectomized systemic lupus erythematosus-susceptible LDLr(-/-) mice.
Not available
S-EPMC3618855 | biostudies-literature
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