Sort   by:  
 Page size 
MetabolomicsOrganism-Wide Analysis of Sepsis Reveals Mechanisms of Systemic Inflammation
Not available
ORGANISM(S): Mus musculus 
ST002455 | MetabolomicsWorkbench
MetabolomicsTranscobalamin 2 orchestrates monocyte proliferation and TLR4-driven inflammation in systemic lupus erythematosus via folate one-carbon metabolism

BACKGROUND: SLE is a complex autoimmune disease with deleterious effects on various organs. Accumulating evidence has shown abnormal vitamin B12 and one-carbon flux contribute to immune dysfunction. Transcobalamin II (TCN2) belongs to the vitamin B12-binding protein family respon...

2024-05-28 | MTBLS9136 | MetaboLights
MetabolomicsMulti-omics reveals taurine-mediated rumen microbial remodeling mitigates high-starch-diet-induced systemic inflammation and oxidative stress in fattening cattle

Background: With the pursuit of rapid intramuscular fat deposition in beef cattle, basal diets have increasingly shifted toward grain-based, energy-dense formulations. However, high-starch dietary regimens may induce host metabolic dysregulation, which is closely linked to both ruminal microbial ...

2025-09-25 | MTBLS13041 | MetaboLights
MetabolomicsComparative 1H-NMR Lipoprotein Profiling of Rheumatoid Arthritis and Systemic Lupus Erythematosus Patients Highlights Disease-Specific Lipoprotein Dysregulation

Rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) are systemic autoimmune diseases associated with increased cardiovascular risk and metabolic alterations. We applied 1H-NMR spectroscopy to profile lipoproteins and metabolites in women with RA, SLE, and healthy controls. Both RA an...

2026-02-02 | MTBLS13820 | MetaboLights
MetabolomicsUnderstanding systemic and local inflammation induced by nasal polyposis: role of the allergic phenotype (part-I)
Not available
ORGANISM(S): Homo sapiens 
ST001733 | MetabolomicsWorkbench
MetabolomicsSystemic host inflammation induces stage-specific transcriptomic modification and slower maturation in malaria parasites (part II)
Not available
ORGANISM(S): Mus musculus 
ST001900 | MetabolomicsWorkbench
MetabolomicsUnderstanding systemic and local inflammation induced by nasal polyposis: role of the allergic phenotype (part-II)
Not available
ORGANISM(S): Homo sapiens 
ST001734 | MetabolomicsWorkbench
MetabolomicsSystemic host inflammation induces stage-specific transcriptomic modification and slower maturation in malaria parasites (part I)
Not available
ORGANISM(S): Mus musculus 
ST001899 | MetabolomicsWorkbench
MetabolomicsSystemic Inflammation Induces Cholestasis via Upregulating a Short Variant of FTO to Remove the m6A Methylation in the 3’-UTR of Cyp7b1 mRNAs in liver
The cholestasis frequently occurs in patients with inflammatory processes. However, the mechanisms of inflammation in inducing cholestasis are still unclear. Here, by using lipopolysaccharide (LPS)-induced cholestasis mouse models, we found that most genes encoding enzymes responsible for bile acid ...
2025-11-07 | MTBLS10713 | MetaboLights
MetabolomicsSurvival of the littlest: Navigating sepsis diagnosis beyond inflammation in preterm neonates
Background Sepsis diagnosis in preterm neonates is challenging due to symptom overlap with non-infectious inflammatory conditions, and slow, unreliable diagnostic practices. This study aims to identify metabolic biomarkers to elucidate sepsis pathophysiology, and enable timely, accurate diagnosis, w...
2025-07-07 | MTBLS10665 | MetaboLights
Sort   by:  
 Page size