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TranscriptomicsTranscription profiling by array of human monocyte-derived dendritic cells treated with 1,25-dihydroxyvitamin D3
We have carried out global gene expression analysis to clarify the interrelationship between 1,25-dihydroxyvitamin D3 and differentiation-driven gene expression patterns in developing human monocyte-derived dendritic cells. Monocytes were treated with 10 nM 1,25-dihydroxyvitamin D3 or vehicle 14 hou...
ORGANISM(S): Homo sapiens 
2009-02-21 | E-GEOD-13762 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of genes regulated by RXR and its partners in monocyte-derived dendritic cells
CD14+ human monocytes differentiating into DCs in the presence of IL4 and GM-CSF were treated with agonists for RXR and its partners or vehicle 18 hours after plating (experiment with RXR and permissive partners, donor 1-3) or 14 hours after plating (experiment with nonpermissive partners, donor 4-6...
ORGANISM(S): Homo sapiens 
2010-09-01 | E-GEOD-23073 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of dendritic cell subtypes
In this study transcriptome profiling of dendritic cell subtypes was performed using various human dendritic cells. Monocyte-derived DC: CD14+ monocytes were obtained from buffy coats by Ficoll - gradient centrifugation and immunomagnetic cell separation using anti-CD14-conjugated microbeads. Monoc...
ORGANISM(S): Homo sapiens 
2010-10-27 | E-GEOD-23618 | biostudies-arrayexpress
TranscriptomicsCOPD-Specific Gene Expression Signatures of Alveolar Macrophages as well as Peripheral Blood Monocytes Overlap and Correlate with Lung Function
Rationale: Chronic Obstructive Pulmonary Disease (COPD) is considered a chronic inflammatory disease characterized by progressive airflow limitation and also has significant extrapulmonary (systemic) effects that lead to comorbid conditions. Very little is known about the pathomechanism of the disea...
ORGANISM(S): Homo sapiens 
2011-04-18 | E-GEOD-16972 | biostudies-arrayexpress
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