T-rex 293 - OmicsDI

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Homo sapiens strain:T-REx-293

Homo sapiens strain:T-REx-293 Raw sequence reads

PRJNA312357 | ENA

SNP microarray of T-REx-293-based clones overexpressing the DNA cytosine deaminase APOBEC3B

A conditional and isogenic system for APOBEC3B (A3B) induction in T-REx-293 cells. Cells were engineered to express doxycycline-inducible A3B-eGFP or eGFP constructs and subjected to 10 rounds of A3B-eGFP exposure causing 80-90% cell death. Control pools (eGFP) were subjected to parallel rounds of n...

ORGANISM(S): Homo sapiens

2016-06-30 | E-GEOD-78710 | biostudies-arrayexpress

RNA-Seq of WT Flp-In T-REx 293 and UPF3B knockout cell lines with additional siRNA-mediated control or UPF3A knockdowns

UPF3A and UPF3B are paralogous genes in human cells that are involved in the nonsense-mediated decay (NMD) pathway. NMD is a cellular quality control mechanism that monitors mRNAs during translation. Aberrant translation due to features such as the presence of a premature stop codon downstream on an...

ORGANISM(S): Homo sapiens

2022-04-25 | E-MTAB-10711 | biostudies-arrayexpress

RNA-Seq of control and RNPS1 knockdown with or without RNPS1 wildtype or RNPS1-RRM domain rescue in Flp-In T-REx 293 cells

RNPS1 is a splicing regulatory protein and a component of the ASAP/PSAP complex, which is associated with the exon junction complex and modulates alternative splicing. It was previously postulated that the isolated RRM domain of RNPS1 in complex with ASAP/PSAP is able to regulate certain alternative...

ORGANISM(S): Homo sapiens

2022-05-06 | E-MTAB-10770 | biostudies-arrayexpress

RNA-Seq of WT Flp-In T-REx 293, UPF3B knockout and UPF3A-UPF3B double knockout cell lines with additional siRNA-mediated control or UPF3B knockdowns

ORGANISM(S): Homo sapiens

2022-04-25 | E-MTAB-10716 | biostudies-arrayexpress

RNA-Seq of WT Flp-In T-REx 293, UPF3A knockout and UPF3A overexpression cell lines in part with additional siRNA-mediated control or UPF3B knockdowns

ORGANISM(S): Homo sapiens

2022-08-31 | E-MTAB-10718 | biostudies-arrayexpress

FAM98C KO validation in HEK Flp-In T-REx 293 cells.

Validation of a FAM98C KO in HEK Flp-In T-REx 293 cells by quantifying the occurrence of FAM98C-specific peptides in whole cell lysates with LC-MSMS. WT HEK Flp-In T-REx 293 cells were used as control.

ORGANISM(S): Homo sapiens (Human)

2026-06-08 | PXD076694 | Pride

NPAS3-HEK293-circadian-Illumina

The fragments of FLNPAS3 and DeltaNPAS3 were transferred into a similar TET-inducible expression plasmid and transfected into HEK293 [T-REx-293] cells (Invitrogen). At the zero hour time-point, cells were shifted into a serum-rich medium plus tetracycline in order to induce circadian cycling and NPA...

ORGANISM(S): Homo sapiens

2011-10-03 | E-TABM-1079 | biostudies-arrayexpress

RNA-seq of engineered T-REx-293 cell lines expressing standard or immunoproteasome

PRJEB104183 | ENA

Monosome and disome profiling of Flag-STAU1 Flp-In 293 T-REx cells

Monosome and disome profiling was performed on Flag-STAU1 Flp-In 293 T-REx to study the causes of ribosomal collisions, and whether this may be modulated by the presence/absence of Staufen-1. Cells were treated with either an siRNA targeting STAU1 transcript (4x samples) or a control siRNA (2x sam...

ORGANISM(S): Homo sapiens

2023-04-30 | E-MTAB-9669 | biostudies-arrayexpress

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