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Bacteria deploy diverse antiphage defense systems, including small bioactive molecules providing protection at the multicellular level. DNA-intercalating anthracyclines such as daunorubicin exhibit broad antiphage activity, but the underlying mechanism had remained elusive. Here, we systematically s...
ORGANISM(S): Escherichia coli Escherichia phage HildyBeyeler 
2026-05-13 | PXD070949 | Pride
This study analysed the temporal transcriptional response of L. lactis UC509.9 undergoing infection with either Tuc2009 or c2, representing phages of two different species (P335 and c2, respectively) of the family Siphoviridae. For the first time, to our knowledge, both DNA microarrays of the host a...
ORGANISM(S): Lactococcus lactis subsp. cremoris UC509.9 
Bacterial Schlafen proteins mediate phage defense [phage genome seq]
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