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ModelsHayashi2013 - TNF-induced Signaling Dynamics (Model A)
Hayashi2013 - TNF-induced Signaling Dynamics Model (Model A) Tumor necrosis factor (TNF) plays a crucial role in inflammation and is associated with diseases such as rheumatoid arthritis and cancer. While TNF signaling pathways are well studied, targeted regulation of proinflammatory responses rem...
2025-02-19 | MODEL2502170001 | BioModels
ModelsHayashi2013 - Extended TNF-induced Signaling with Gene Expression Dynamics (Model B)
Hayashi2013 - Extended TNF-induced Signaling with Gene Expression Dynamics (Model B) Tumor necrosis factor (TNF) plays a crucial role in inflammation and is associated with diseases such as rheumatoid arthritis and cancer. While TNF signaling pathways are well studied, targeted regulation of proin...
2025-02-19 | MODEL2502170002 | BioModels
TranscriptomicsGene expression profile of human epidermoid carcinoma KB cells that overexpress thymidine phosphorylase
Thymidine phosphorylase (TP) catalyzes the reversible phosphorolysis of thymidine, deoxyuridine, and their analogs to the respective bases and 2-deoxy-D-ribose-1-phosphate. TP is identical to platelet-derived endothelial cell growth factor (PD-ECGF). TP was reported to induce many angiogenic factors...
ORGANISM(S): Homo sapiens 
2014-08-03 | E-GEOD-31467 | biostudies-arrayexpress
MetabolomicsMetabolic profiling of prostate cancer in skeletal microenvironments identifies G6PD as a key mediator of growth and survival

The spread of cancer to bone is invariably fatal, with complex cross-talk between tumor cells and the bone microenvironment responsible for driving disease progression. By combining in silico analysis of patient datasets with metabolomic profiling of prostate cancer cells cultured with bone cells...

2024-08-19 | MTBLS3973 | MetaboLights
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