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Abe8e TadA directed evolution campaign sequencing
Cell-type specific transcriptional profiling is key to understanding cell fate specification and function. In order to achieve this it has been necessary, to date, to isolate specific cell types from complex tissues. We have developed 'TaDa', a technique that enables cell-specific profiling without ...
ORGANISM(S): Drosophila melanogaster 
Adenosine-to-inosine A-to-I mRNA editing alters genetic information post-transcriptionally and can impact protein sequence and function, yet its regulation in bacteria remains unclear. Here, we profiled A-to-I editing in Escherichia coli across nutrient-rich LB and minimal M9 media and different gro...
ORGANISM(S): Bacteria Escherichia coli (strain K12) 
2026-03-24 | PXD075028 | Pride
Targeted DamID (TaDa) is an increasingly popular method of generating cell-type specific DNA binding profiles in vivo. Although sensitive and versatile, TaDa requires the generation of new transgenic fly lines for every protein that is profiled, which is both time-consuming and costly. Here, we desc...
ORGANISM(S): Drosophila melanogaster 
2021-01-31 | GSE159632 | GEO
This project’s aim was to compare the transcriptional profiles of olfactory sensory neurons in Drosophila melanogaster in order to identify novel genes that specify neuron-specific functions/phenotypes or may otherwise be involved in the development of the olfactory system. The isolation of suffic...
ORGANISM(S): Drosophila melanogaster 
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