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This model is described in the article: Glucose 6-phosphate accumulates via phosphoglucose isomerase inhibition in heart muscle. Karlstaedt, A and Khanna, R and Thangam, M and Taegtmeyer, H Circulation Research (2019) The ...
2019-11-14 | MODEL1910170001 | BioModels
The Cdk7/cyclin H/menage-a-trois 1 (MAT1) heterotrimer has proposed functions in transcription as the kinase component of basal transcription factor TFIIH and is activated in adult hearts by hypertrophic pathways. Using cardiac-specific Cre, we ablated MAT1 in myocardium. Despite reduced Cdk7 activi...
ORGANISM(S): Mus musculus 
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