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TranscriptomicsTranscription profiling of mouse brain Homer1a-expressing cells after sleep deprivation
To gain insight into the molecular changes of sleep need, this study addresses gene expression changes in a subpopulation of neurons selectively activated by sleep deprivation. Whole brain expression analyses after 6h sleep deprivation clearly indicate that Homer1a is the best index of sleep need, c...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9443 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse brain from 3 inbred strains after sleep deprivation
This SuperSeries is composed of the following subset Series:; GSE9441: The effect of sleep deprivation on gene expression in the brain and the liver of three inbred mouse strains; GSE9442: Molecular correlates of sleep deprivation in the brain of three inbred mouse strains in an around-the-clock exp...
ORGANISM(S): Mus musculus 
2008-06-17 | E-GEOD-9444 | biostudies-arrayexpress
TranscriptomicsSleep in a dish: key electrophysiological, molecular, and metabolic signatures of sleep and wakefulness revealed in primary cortical cultures
Although at the organismal level sleep is defined as a behavioral state, at the level of the cerebral cortex sleep has a distinct local and use-dependent aspect. This observation raises the question whether sleep is a functional property of a complex brain or occurs at the level of neuronal assembli...
ORGANISM(S): Mus musculus 
2012-08-31 | E-GEOD-33491 | biostudies-arrayexpress
TranscriptomicsGene profiling within the orexin-producing neurons
Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness and attacks of muscle atonia triggered by strong emotions (cataplexy). The best biological marker of narcolepsy is orexin deficiency with dramatic loss in hypothalamic orexin-producing neurons. Together with a tight HLA and...
ORGANISM(S): Mus musculus 
2010-02-24 | E-GEOD-17617 | biostudies-arrayexpress
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