Sort   by:  
 Page size 
TranscriptomicsDigital gene expression tag profiling of digit morphologies in bats
As the only truly flying mammals, bats use their unique wing formed from elongated digits connected by membranes to power their flight. The forelimb of bats consists of four elongated digits (digits II-V) and one shorter digit (digit I) that is morphologically similar to the hindlimb digits. Elongat...
ORGANISM(S): Myotis ricketti 
2010-12-06 | E-GEOD-20038 | biostudies-arrayexpress
GenomicsComprehensive Long Span Paired-End-Tag Mapping Reveals Characteristic Patterns of Structural Variations in Epithelial Cancer Genomes
Somatic genome rearrangements are thought to play important roles in cancer development. We optimized a long span paired-end-tag (PET) sequencing approach using 10 Kb genomic DNA inserts to study human genome structural variations (SVs). The use of 10 Kb insert size allows the identification of brea...
ORGANISM(S): Homo sapiens 
2011-04-06 | E-GEOD-26954 | biostudies-arrayexpress
GenomicsLong Span DNA Paired-End-Tag (DNA-PET) Sequencing Strategy for the Interrogation of Genomic Structural Mutations
Structural variations (SVs) contribute significantly to the variability of the human genome and extensive genomic rearrangements are a hallmark of cancer. Genomic DNA paired-end-tag (DNA-PET) sequencing is an attractive approach to identify genomic SVs. The current application of PET sequencing with...
ORGANISM(S): Homo sapiens 
2012-10-04 | E-GEOD-32674 | biostudies-arrayexpress
TranscriptomicsAn Atlas of Bovine Gene Expression Reveals Novel Distinctive Tissue Characteristics and Evidence for Improving Genome Annotation
Background: A comprehensive transcriptome survey, or "gene atlas", provides information essential for a complete understanding of the genomic biology of an organism. We present an atlas of RNA abundance for 92 adult, juvenile and fetal cattle tissues and 3 cattle cell lines. Results: The ...
ORGANISM(S): Bos taurus 
2010-09-28 | E-GEOD-21544 | biostudies-arrayexpress
TranscriptomicsCUT&Tag for S9.6 in DIS3-depleted cells
CUT&Tag was performed to identify the effect of DIS3 depletion on DNA:RNA hybrids genome-wide. DIS3-AID HCT116 cells were treated with either Auxin (for rapid depletion of DIS3) or DMSO (control). CUT&Tag was performed targeting DNA:RNA hybrids using the CUT&Tag-IT® R-loop Assay Kit (Active Motive) ...
ORGANISM(S): Homo sapiens 
2026-08-03 | E-MTAB-17179 | biostudies-arrayexpress
TranscriptomicsCUT&Tag of H3K27Ac of HCT26-1T: Control and GSK126
CUT&Tag for H3K27Ac; Colorectal cancer patient derived organoids, HCT26-1T; drug experiment of control vs GSK126.
ORGANISM(S): Homo sapiens 
2025-11-20 | E-MTAB-16203 | biostudies-arrayexpress
TranscriptomicsIdentification of stromally expressed molecules in the prostate by Tag profiling of cancer-associated fibroblasts, normal fibroblasts and fetal prostate
The stromal microenvironment plays key roles in prostate development and cancer. Cancer associated fibroblasts (CAFs) and other stromal cells stimulate tumourigenesis via several mechanisms including the expression of pro-tumourigenic factors. Mesenchyme (embryonic stroma) controls prostate organoge...
ORGANISM(S): Homo sapiens 
2011-10-22 | E-GEOD-25018 | biostudies-arrayexpress
TranscriptomicsCUT&Tag for RNAPII-Ser2p or RNAPII-Ser5p in DIS3-depleted cells
CUT&Tag was performed to identify the effect of DIS3 depletion on RNAPII in response to UV irradiation. DIS3-AID HCT116 cells were treated with either Auxin (for rapid depletion of DIS3) or DMSO (control) before irradiation with 8 J/m2 UVC. CUT&Tag was performed targeting RNAPII-Ser2p or RNAPII-Ser5...
ORGANISM(S): Homo sapiens 
2026-08-03 | E-MTAB-16280 | biostudies-arrayexpress
TranscriptomicsGlobal genomic mapping, in Saccharomyces cerevisiae, of new suppressor alleles of the RNA polymerase I subunit rpa49 deletion.
In the yeast saccharoryces cerevisiae, RPA49 full-deletion mutants show a strong growth defect at 30°C and are unable to grow at 25°C. However, spontaneous suppressors that restore growth at 25°C are observed. We attend to identified new suppressor alleles after UV treatment. To mapped the genomic l...
ORGANISM(S): Saccharomyces cerevisiae 
2019-12-31 | E-MTAB-7831 | biostudies-arrayexpress
TranscriptomicsTag profiling of genes from two Pachycladon species
Tag profiling and expression analysis of genes from Pachycladon enysii and Pachycladon fastigiatum
ORGANISM(S): Pachycladon fastigiatum 
2011-06-01 | E-MTAB-610 | biostudies-arrayexpress
Sort   by:  
 Page size