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TranscriptomicsEpstein-Barr virus maintains lymphomas via its miRNAs
EpsteinM-bM-^@M-^PBarr virus (EBV) has evolved exquisite controls over its host cells, human B lymphocytes, not only directing these cells during latency to proliferate and thereby expand the pool of infected cells, but also to survive and thereby persist for the lifetime of the infected individual....
ORGANISM(S): Homo sapiens 
2013-04-30 | E-GEOD-44769 | biostudies-arrayexpress
TranscriptomicsATAC-seq experiment in two versions of Raji cells with inducible BZLF1 variants prior to and after induction of EBV's lytic cycle by doxycycline.
The aim of the experiment was to identify accessible (open) chromatin regions in the genome prior to and post induction of EBV's lytic phase by the BZLF1 protein. Two versions of BZLF1 were employed: full-length and activation-domain (AD)-truncated BZLF1 non-induced and induced for 15 h. The experim...
ORGANISM(S): Homo sapiens 
2019-04-01 | E-MTAB-7789 | biostudies-arrayexpress
TranscriptomicsChIP-seq against BZLF1 in Raji cells (EBV, Human Herpesvirus 4, GenBank accession KF717093).
ChIP-seq experiments with the antibody BZ1 directed against the EBV protein BZLF1 prior to and 15 hours post induction with doxycycline (100 ng/ml). The doxycycline regulated conditional BZLF1 allele is encoded by an inducible plasmid stably introduced into Raji cells. Experiments were performed as ...
ORGANISM(S): Homo sapiens 
2019-04-01 | E-MTAB-7788 | biostudies-arrayexpress
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