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TranscriptomicsExpression of brain gene at P4 and P10 post-coïtus in the rat, after protein restriction of the mother regimen during gestation
Total brain was collected from newborn rats that were growth-restricted obtained by feeding the females a low-protein diet during pregnancy. The model was extensively described in Buffat et al, J. Pathology 2007, and Zana-Taieb et al, J. Pathology, 2015.
ORGANISM(S): Rattus norvegicus 
2016-10-14 | E-MTAB-4646 | biostudies-arrayexpress
TranscriptomicsSeparated transcriptome analysis of microglial cells and oligodendrocytes in the brain of P4 rats, in intra-uterine growth restriction or control conditions
Females were exposed during pregnancy to a normal or low protein diet (as described in Buffat et al, J. Pathol, 2007 and Zana-Taieb et al, J. Pathol, 2015). Brains cells were dissociated using the Neural Tissue Dissociation Kit of Miltenyi Biotec,in the presence of papain. Then Magnetic Bead couple...
ORGANISM(S): Rattus norvegicus 
2016-10-14 | E-MTAB-4647 | biostudies-arrayexpress
TranscriptomicsEffects of low protein diet-induced Intra-Uterine Growth Restriction in Rat microglial brain cells at P0 and P4. Double Hit at P4 with subclinical doses of IL1B
Female rats were exposed during pregnancy to a normal or low protein diet (as described in Bufffat et al, J. Pathol, 2007 and Zana-Taieb et al, J. Pathol, 2015; Rideau Batista Novais, Glia, 2016), then injected with low doses of interleukin1B (20µg/kg) at P1, for the P4 samples. LPD effects were als...
ORGANISM(S): Rattus norvegicus 
2018-12-31 | E-MTAB-6630 | biostudies-arrayexpress
TranscriptomicsEffects of low protein diet-induced Intra-Uterine Growth Restriction in Rat Whole brain at 28 days, and on microglial brain cells at P4. Double Hit with subclinical doses of IL1B, Rescue by Carbetocin treatment.
Female rats were exposed during pregnancy to a normal or low protein diet (as described in Bufffat et al, J. Pathol, 2007 and Zana-Taieb et al, J. Pathol, 2015; Rideau Batista Novais, Glia, 2016), then injected with low doses of interleukin1B (20µg/kg) at P1, for the P4 samples. Brain samples were ...
ORGANISM(S): Rattus norvegicus 
2018-12-30 | E-MTAB-6631 | biostudies-arrayexpress
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