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TranscriptomicsDeciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection.
Identification of genetic polymorphisms associated with inter-individual variation in immune response to Mycobacterium tuberculosis infection. We performed a genome-wide mapping study of loci that are associated with functional variation in immune response to MTB. Specifically, we characterized tran...
ORGANISM(S): Homo sapiens 
2011-12-06 | E-GEOD-34151 | biostudies-arrayexpress
TranscriptomicsMycobacterial infection induces a specific human innate immune response
The innate immune system provides the first response to pathogen infection and orchestrates the activation of the adaptive immune system. Though a large component of the innate immune response is common to all infections, pathogen-specific innate immune responses have been documented as well. The in...
ORGANISM(S): Homo sapiens 
2015-03-31 | E-GEOD-67427 | biostudies-arrayexpress
TranscriptomicsA Genomic Portrait of the Genetic Architecture and Regulatory Impact of microRNA Expression in Response to Infection
Identification of changes in microRNA expression, remodelling of relationships between microRNA and mRNA expression levels, and genetic polymorphisms associated with inter-individual variation in the dendritic cell immune response to Mycobacterium tuberculosis infection. We characterised genome-wide...
ORGANISM(S): Homo sapiens 
2014-01-17 | E-GEOD-49951 | biostudies-arrayexpress
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