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TranscriptomicsPathway Profiling of Replicative and Induced Senescence
RNA-seq was performed on LFS MDAH041 cells that were young (PD10-12), aging (PD17-19) and replicatively senescent (PD28-30), as well as spontaneously immortal cells and cells that were induced into senescence or quiescence, in order to profile the pathways common in all 4 types of sensecence and th...
ORGANISM(S): Homo sapiens 
2015-02-01 | E-GEOD-60340 | biostudies-arrayexpress
TranscriptomicsGene profiles of pathway interference downstream neurofibromin signaling
Malignant peripheral nerve sheath tumor (MPNST) is a type of soft tissue sarcoma that occurs in carriers of mutations in the neurofibromatosis type I gene (Nf1) as well as sporadically.　Plexiform neurofibromas in NF1 patients have a significant risk of developing into MPNSTs leading to increased mor...
ORGANISM(S): Homo sapiens 
2013-03-15 | E-GEOD-39764 | biostudies-arrayexpress
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