Sort   by:  
 Page size 
GenomicsChIP-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Gene expression is balanced by transcription and mRNA degradation. Shortening of polyadenosine (poly(A)) tails (deadenylation) is the initial step in the decay of most mRNAs. However, the mechanism by which deadenylation controls mRNA expression is not fully understood. This experiment aimed to dete...
ORGANISM(S): Mus musculus 
2020-03-30 | E-MTAB-5887 | biostudies-arrayexpress
TranscriptomicsRIP-seq of livers in C57BL/6J mice with antibodies against Cnot3, Ago2, and BRF1
Shortening of polyadenosine (poly(A)) tails (deadenylation) is the initial step in the decay of most mRNAs. The CCR4-NOT complex is the major deadenylase in mammals. Interaction of Cnot1 with RNA binding proteins, including the miRNA-induced silencing complex (miRISC), which includes Argonaute (Ago)...
ORGANISM(S): Mus musculus 
2020-03-30 | E-MTAB-6941 | biostudies-arrayexpress
TranscriptomicsRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Gene expression is balanced by transcription and mRNA degradation. Shortening of polyadenosine (poly(A)) tails (deadenylation) is the initial step in the decay of most mRNAs. However, the mechanism by which deadenylation controls mRNA expression is not fully understood. This experiment aimed to dete...
ORGANISM(S): Mus musculus 
2020-03-30 | E-MTAB-5901 | biostudies-arrayexpress
TranscriptomicsExpression profile in HEK293T cells transfected with control or ZAPS expression vector
Analysis of HEK293T cells overexpressing ZAPS (zinc finger antiviral protein, short form; NP_078901), which is a member of the PARP (poly (ADP-ribose) polymerase)-superfamily. Results of gene profiles provide insight into the role of ZAPS in innate immunity. HEK293T cells were transfected with ZAPS ...
ORGANISM(S): Homo sapiens 
2010-12-22 | E-GEOD-25471 | biostudies-arrayexpress
ProteomicsPHD3-mediated HIV-2 Vpx peptide hydroxylation
This dataset contains comparative mass spectrometry analysis investigating proline hydroxylation of synthetic HIV-2 Vpx peptides under two conditions: with and without PHD3 enzyme treatment. The analysis was performed using a high-resolution mass spectrometer coupled to a nano-LC system. The dataset...
ORGANISM(S): Human Immunodeficiency Virus 2 
2025-04-03 | PXD059242 | JPOST Repository
ProteomicsCross-linking MS analysis of HIV-2 Vpx-PHD3 protein interaction
This dataset presents chemical crosslinking mass spectrometry (CL-MS) analysis of protein-protein interactions between HIV-2 Vpx and PHD3. The experimental data includes MS spectra obtained from protein complexes comprising recombinant Vpx and PHD3 crosslinked using DSBU under physiological conditio...
ORGANISM(S): Human Immunodeficiency Virus 2 
2025-04-03 | PXD059241 | JPOST Repository
Sort   by:  
 Page size