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TranscriptomicsGene expressions of CD4+ T cells in each developmental stages
The development of T cells has been characterized as taking place over three stages: naïve (Tn), central memory (Tcm), and effector memory (Tem) cells. Recently, stem cell memory T cells (Tscm) were found to be the least-developed memory subset. We performed detailed analysis of the gene expression ...
ORGANISM(S): Homo sapiens 
2015-05-12 | E-GEOD-61697 | biostudies-arrayexpress
TranscriptomicsIdentification of baseline gene expression signatures predicting therapeutic responses to three biologic agents in rheumatoid arthritis: a retrospective observational study
The aim of this study was to identify the specific molecular biological features predicting the therapeutic outcomes of three bDMARDs, infliximab (IFX), tocilizumab (TCZ), and abatacept (ABT) by studying blood gene expression signature of patients prior to biologic treatment in a unified test platfo...
ORGANISM(S): Homo sapiens 
2016-07-21 | E-GEOD-78068 | biostudies-arrayexpress
TranscriptomicsmRNA expression profile in peripheral blood cells of RA patients following treatment with an anti-TNFa mAb, infliximab
Objectives: We monitored the mRNA expression profiles of peripheral blood cells during treatment with a tumor necrosis factor-a inhibitor, infliximab, in patients with rheumatoid arthritis (RA). Using a DNA microarray analysis, we demonstrated a unique set of genes, with distinct baseline and post-t...
ORGANISM(S): Homo sapiens 
2007-10-09 | E-GEOD-8350 | biostudies-arrayexpress
UnknownGenetic insights into ossification of the posterior longitudinal ligament of the spine.
Not available
S-EPMC10353864 | biostudies-literature
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