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ProteomicsCrosslinking mass spectrometry of the p300 catalytic core complexed with the nucleosome
p300 is a histone acetyltransferase that associates with crucial biological processes. p300 acetylates all four histones in the nucleosome, a basic unit of chromatin, and alters chromatin structure and dynamics. In this study, we performed structural and biochemical analysis to understand the nucleo...
ORGANISM(S): Homo Sapiens (human) 
2022-06-29 | PXD033804 | JPOST Repository
ProteomicsNucleosome binding by the pioneer transcription factor OCT4
The nucleosome is a fundamental unit of chromatin in eukaryotes, and generally prevents the binding of transcription factors to genomic DNA. Pioneer transcription factors overcome the nucleosome barrier, and bind their target DNA sequences in chromatin. OCT4 is a representative pioneer transcription...
ORGANISM(S): Homo Sapiens (human) 
2020-05-13 | PXD019160 | JPOST Repository
TranscriptomicsThe use of non-amplified RNA samples for gene expression analysis by sensitive microarray.
Gene expression profiles were compared based on the rounds of sample RNA amplification procedure. The intra- and inter-method reproducibility was shown by comparing gene expression profiles from two micoarray data. For the repeatability, CVs calculated from multiple microarray data were compared bet...
ORGANISM(S): Homo sapiens 
2011-07-27 | E-GEOD-30945 | biostudies-arrayexpress
GenomicsDBA_250K - samples
DBA case samples using 250K Nsp
EGAD00010000096 | EGA
GenomicsCopy number analysis of Diamond-Blackfan Anemia (DBA) using SNP array
Diamond–Blackfan anemia (DBA), is a rare congenital anemia that usually presents in infancy. About fifty percent of DBA patients possess mutations in ribosomal protains (RPs). In this study, we performed genomic copy number analysis using SNP arrays for 27 Japanese DBA patients to detect genomic c...
EGAS00000000105 | EGA
GenomicsCancer Genomics Project DBA Data Access Committee
Data Access Committee EGAC01000000005
EGAC01000000005 | EGA
TranscriptomicsMicroRNA markers for the diagnosis of pancreatic and biliary tract cancers
MicroRNAs from serum samples could detect pancreatic and biliary tract cancer patients more accurately than other traditional markers. Prospective miRNA markers for pancreatic/biliary tract cancer were selected in the training cohort. Using these miRNAs, discriminant analysis was performed, and the ...
ORGANISM(S): Homo sapiens 
2015-03-01 | E-GEOD-59856 | biostudies-arrayexpress
Proteomics,MultiomicsHematopoietic stem cells (HSCs)
G0 marker-separation of dormant and active hematopoietic stem cells reveals dormancy regulation by basal cytoplasmic calcium
ORGANISM(S): Mus Musculus (mouse) 
2019-12-19 | PXD012093 | JPOST Repository
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