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UnknownEffect of ruxolitinib therapy on myelofibrosis-related symptoms and other patient-reported outcomes in COMFORT-I: a randomized, double-blind, placebo-controlled trial.
Not available
S-EPMC4979167 | biostudies-literature
TranscriptomicsAcquired genomic copy number aberrations and survival in chronic lymphocytic leukemia
Genomic aberrations are of predominant importance to the biology and clinical outcome of patients with chronic lymphocytic leukemia (CLL), and FISH-based genomic risk classifications are routinely used in clinical decision making in CLL. One of the known limitations of CLL FISH is the inability to ...
ORGANISM(S): Homo sapiens 
2011-11-29 | E-GEOD-30777 | biostudies-arrayexpress
GenomicsIdentification of Recurrent NAB2-STAT6 Gene Fusions in Solitary Fibrous Tumor by Integrative Sequencing

Transcriptome sequencing of solitary fibrous tumors / hemangiopericytomas from a variety of anatomic sites revealed recurrent gene fusions between two genes, NAB2 and STAT6. All SFTs examined exhibited an in-frame fusion transcript encoding a fusion protein containing the EGR1 interaction domain ...

phs000567.v1.p1 | EGA
TranscriptomicsNF1 inactivation in adult acute myelogenous leukemia
Purpose: This study was conducted to identify novel genes with importance to the biology of adult acute myelogenous leukemia (AML). Conclusions: NF1 null states are present in 7/95=7% of adult AML and delineate a disease subset that could be preferentially targeted by Ras or mTOR-directed therapeut...
ORGANISM(S): Homo sapiens 
2010-12-02 | E-GEOD-21107 | biostudies-arrayexpress
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