Sort   by:  
 Page size 
TranscriptomicsTamoxifen induces expression of immune-response related genes in cultured NHMEC
Administration of tamoxifen (TAM) as breast cancer adjuvant therapy is associated with a 50% reduction in breast cancer risk and an increase in endometrial cancer risk. To investigate underlying mechanisms, we documented TAM-induced gene expression changes in cultured normal human mammary epithelial...
ORGANISM(S): Homo sapiens 
2009-01-29 | E-GEOD-13476 | biostudies-arrayexpress
GenomicsRNA-seq Analysis Reveals Different Drought Tolerance Mechanisms in Two Broadly Adapted Wheat Cultivars ‘TAM 111’ and ‘TAM 112’
RNA-seq Analysis Reveals Different Drought Tolerance Mechanisms in Two Broadly Adapted Wheat Cultivars ‘TAM 111’ and ‘TAM 112’
PRJNA659916 | ENA
UnknownRNA-seq analysis reveals different drought tolerance mechanisms in two broadly adapted wheat cultivars 'TAM 111' and 'TAM 112'.
Not available
S-EPMC7900135 | biostudies-literature
TranscriptomicsExpression data from mouse aorta during and following transient hyperglycaemia
Immediate and early effects of transient hyperglycaemia were examined using fully- reversible transgenic diabetic mice. Transient hyperglycaemia altered expression of 769 arterial genes, of which 200 did not reverse following recovery from hyperglycaemia. Many such genes are known to promote athero...
ORGANISM(S): Mus musculus 
2010-08-09 | E-GEOD-15401 | biostudies-arrayexpress
TranscriptomicsSynergistic activation by p38MAPK and glucocorticoid signaling mediates induction of M2-like tumor-associated macrophages expressing the novel CD20 homolog MS4A8A.
Tumor-associated macrophages (TAMs) represent alternatively activated (M2) macrophages that support tumor growth. Previously, we have described a special LYVE-1(+) M2 TAM subset in vitro and in vivo; gene profiling of this TAM subset identified MS4A8A as a novel TAM molecule expressed in vivo by TAM...
ORGANISM(S): Mus musculus 
2012-05-22 | E-GEOD-38171 | biostudies-arrayexpress
TranscriptomicsHigh-density gene expression analysis of tumor-associated macrophages from mouse mammary tumors
Clinical and experimental evidence indicates that tumor-associated macrophages (TAMs) promote malignant progression. In breast cancer, TAMs enhance tumor angiogenesis, tumor cell invasion, matrix remodeling, and immune suppression against the tumor. In this study, we examined late-stage mammary tumo...
ORGANISM(S): Mus musculus 
2010-06-21 | E-GEOD-18404 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data for xenografted transient abnormal myelopoiesis samples
Transient abnormal myelopoiesis (TAM) is a clonal pre-leukemic disorder that progresses to myeloid leukemia of Down syndrome (ML-DS) through the accumulation of genetic alterations. To investigate the mechanism of leukemogenesis in this disorder, a xenograft model of TAM was established using NOD/Sh...
ORGANISM(S): Homo sapiens 
2013-03-01 | E-GEOD-44739 | biostudies-arrayexpress
UnknownIn vivo two-photon characterization of tumor-associated macrophages and microglia (TAM/M) and CX3CR1 during different steps of brain metastasis formation from lung cancer.
Not available
S-EPMC8479202 | biostudies-literature
GenomicsCharacterization of tumor associated macrophages (TAM) in the tumor microenvironment of human melanoma
Characterization of tumor associated macrophages (TAM) in the tumor microenvironment of human melanoma
PRJNA718886 | ENA
GenomicsIntegrative Analyses of Gene Expression and DNA Methylation Profiles in a Breast Cancer Cell Line Model of Tamoxifen-Resistance Indicate a Crucial Role of Cells with Stem-like Properties
Purpose: Development of resistance to tamoxifen is an important clinical issue in the treatment of patients with breast cancer. Tamoxifen resistance may be the result of the acquisition of epigenetic regulation such as DNA methylation within breast cancer cells resulting in changed mRNA expression o...
ORGANISM(S): Homo sapiens 
2014-02-03 | E-GEOD-40665 | biostudies-arrayexpress
Sort   by:  
 Page size